Multigene panel sequencing of established and candidate melanoma susceptibility genes in a large cohort of Dutch non‐CDKN2A/CDK4 melanoma families

Germline mutations in the major melanoma susceptibility gene CDKN2A explain genetic predisposition in only 10–40% of melanoma‐prone families. In our study we comprehensively characterized 488 melanoma cases from 451 non‐CDKN2A/CDK4 families for mutations in 30 established and candidate melanoma susc...

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Detalles Bibliográficos
Autores principales: Potjer, Thomas P., Bollen, Sander, Grimbergen, Anneliese J.E.M., van Doorn, Remco, Gruis, Nelleke A., van Asperen, Christi J., Hes, Frederik J., van der Stoep, Nienke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2019
Materias:
Cancer Genetics and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6590189/
https://www.ncbi.nlm.nih.gov/pubmed/30414346
http://dx.doi.org/10.1002/ijc.31984

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