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Intraductal patient‐derived xenografts of estrogen receptor α‐positive breast cancer recapitulate the histopathological spectrum and metastatic potential of human lesions

Estrogen receptor α‐positive (ER‐positive) or ‘luminal’ breast cancers were notoriously difficult to establish as patient‐derived xenografts (PDXs). We and others recently demonstrated that the microenvironment is critical for ER‐positive tumor cells; when grafted as single cells into milk ducts of...

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Detalles Bibliográficos
Autores principales: Fiche, Maryse, Scabia, Valentina, Aouad, Patrick, Battista, Laura, Treboux, Assia, Stravodimou, Athina, Zaman, Khalil, Dormoy, Valerian, Ayyanan, Ayyakkannu, Sflomos, George, Brisken, Cathrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6590246/
https://www.ncbi.nlm.nih.gov/pubmed/30430577
http://dx.doi.org/10.1002/path.5200