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Impact of cell culture media additives on IgG glycosylation produced in Chinese hamster ovary cells

Glycosylation is a key critical quality attribute for monoclonal antibodies and other recombinant proteins because of its impact on effector mechanisms and half‐life. In this study, a variety of compounds were evaluated for their ability to modulate glycosylation profiles of recombinant monoclonal a...

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Detalles Bibliográficos
Autores principales:	Ehret, Janike, Zimmermann, Martina, Eichhorn, Thomas, Zimmer, Aline
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2019
Materias:	ARTICLES
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6590254/ https://www.ncbi.nlm.nih.gov/pubmed/30552760 http://dx.doi.org/10.1002/bit.26904

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