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Mobile Spinal Schwannoma with a Completely Cystic Appearance

Patient: Female, 48 Final Diagnosis: Spinal schawnnoma Symptoms: Dysuria • leg pain Medication: — Clinical Procedure: — Specialty: Orthopedics and Traumatology OBJECTIVE: Challenging differential diagnosis BACKGROUND: Spinal schwannomas are benign tumors arising from Schwann cells. Although they hav...

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Autores principales: Hamabe, Fumiko, Soga, Shigeyoshi, Imabayashi, Hideaki, Matsunaga, Ayano, Shinmoto, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6590268/
https://www.ncbi.nlm.nih.gov/pubmed/31204384
http://dx.doi.org/10.12659/AJCR.916249
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author Hamabe, Fumiko
Soga, Shigeyoshi
Imabayashi, Hideaki
Matsunaga, Ayano
Shinmoto, Hiroshi
author_facet Hamabe, Fumiko
Soga, Shigeyoshi
Imabayashi, Hideaki
Matsunaga, Ayano
Shinmoto, Hiroshi
author_sort Hamabe, Fumiko
collection PubMed
description Patient: Female, 48 Final Diagnosis: Spinal schawnnoma Symptoms: Dysuria • leg pain Medication: — Clinical Procedure: — Specialty: Orthopedics and Traumatology OBJECTIVE: Challenging differential diagnosis BACKGROUND: Spinal schwannomas are benign tumors arising from Schwann cells. Although they have been well described, tumor movement in the spinal canal is an extremely rare finding, and entirely cystic spinal schwannomas have rarely been reported. This is the first report of a spinal schwannoma that simultaneously exhibited both these unusual features. CASE REPORT: A 48-year-old female presented with dysuria and right leg pain. Initial magnetic resonance imaging (MRI) revealed a well-delineated intradural cystic lesion at the level of L4–S1 vertebrae that was isointense with cerebrospinal fluid on both T1- and T2-weighted images. A follow-up MRI 6 months later showed that the tumor had moved to the level of L2–L4; it also revealed tortuous configuration of nerve roots of the cauda equina. The tumor was resected, and a diagnosis of schwannoma with extensive cystic degeneration was pathologically confirmed. CONCLUSIONS: Various possible mechanisms have been suggested for the mobility of extramedullary tumors. In the present case, MRI findings indicated the cause of the tumor movement might be attributed to the laxity of nerve roots. Besides, it is highly atypical for a schwannoma to present an entirely cystic appearance, and the combination of the 2 extraordinary features made preoperative diagnosis difficult. However, 16 out of 22 (73%) of previously reported mobile spinal tumors were schwannomas, so the differential diagnosis for a mobile spinal tumor should include schwannoma, even when the lesion seems entirely cystic on MRI. To minimize the risk of complications and additional surgical dissection, physicians should acknowledge that spinal tumors can migrate.
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spelling pubmed-65902682019-07-12 Mobile Spinal Schwannoma with a Completely Cystic Appearance Hamabe, Fumiko Soga, Shigeyoshi Imabayashi, Hideaki Matsunaga, Ayano Shinmoto, Hiroshi Am J Case Rep Articles Patient: Female, 48 Final Diagnosis: Spinal schawnnoma Symptoms: Dysuria • leg pain Medication: — Clinical Procedure: — Specialty: Orthopedics and Traumatology OBJECTIVE: Challenging differential diagnosis BACKGROUND: Spinal schwannomas are benign tumors arising from Schwann cells. Although they have been well described, tumor movement in the spinal canal is an extremely rare finding, and entirely cystic spinal schwannomas have rarely been reported. This is the first report of a spinal schwannoma that simultaneously exhibited both these unusual features. CASE REPORT: A 48-year-old female presented with dysuria and right leg pain. Initial magnetic resonance imaging (MRI) revealed a well-delineated intradural cystic lesion at the level of L4–S1 vertebrae that was isointense with cerebrospinal fluid on both T1- and T2-weighted images. A follow-up MRI 6 months later showed that the tumor had moved to the level of L2–L4; it also revealed tortuous configuration of nerve roots of the cauda equina. The tumor was resected, and a diagnosis of schwannoma with extensive cystic degeneration was pathologically confirmed. CONCLUSIONS: Various possible mechanisms have been suggested for the mobility of extramedullary tumors. In the present case, MRI findings indicated the cause of the tumor movement might be attributed to the laxity of nerve roots. Besides, it is highly atypical for a schwannoma to present an entirely cystic appearance, and the combination of the 2 extraordinary features made preoperative diagnosis difficult. However, 16 out of 22 (73%) of previously reported mobile spinal tumors were schwannomas, so the differential diagnosis for a mobile spinal tumor should include schwannoma, even when the lesion seems entirely cystic on MRI. To minimize the risk of complications and additional surgical dissection, physicians should acknowledge that spinal tumors can migrate. International Scientific Literature, Inc. 2019-06-17 /pmc/articles/PMC6590268/ /pubmed/31204384 http://dx.doi.org/10.12659/AJCR.916249 Text en © Am J Case Rep, 2019 This work is licensed under Creative Common Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0 (https://creativecommons.org/licenses/by-nc-nd/4.0/) )
spellingShingle Articles
Hamabe, Fumiko
Soga, Shigeyoshi
Imabayashi, Hideaki
Matsunaga, Ayano
Shinmoto, Hiroshi
Mobile Spinal Schwannoma with a Completely Cystic Appearance
title Mobile Spinal Schwannoma with a Completely Cystic Appearance
title_full Mobile Spinal Schwannoma with a Completely Cystic Appearance
title_fullStr Mobile Spinal Schwannoma with a Completely Cystic Appearance
title_full_unstemmed Mobile Spinal Schwannoma with a Completely Cystic Appearance
title_short Mobile Spinal Schwannoma with a Completely Cystic Appearance
title_sort mobile spinal schwannoma with a completely cystic appearance
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6590268/
https://www.ncbi.nlm.nih.gov/pubmed/31204384
http://dx.doi.org/10.12659/AJCR.916249
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