Cargando…

Increased autocrine interleukin‐6 production is significantly associated with worse clinical outcome in patients with chronic lymphocytic leukemia

Chronic lymphocytic leukemia (CLL) remains incurable with current standard therapy. We have previously reported that an increased expression of interleukin‐6 (IL‐6) receptor CD126 leads to resistance of CLL cells to chemotherapy and worse prognosis for patients with CLL. In this study, we determine...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Hua‐Qing, Jia, Li, Li, Yu‐Ting, Farren, Timothy, Agrawal, Samir G., Liu, Feng‐Ting
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2019
Materias:	Original Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6590298/ https://www.ncbi.nlm.nih.gov/pubmed/30623437 http://dx.doi.org/10.1002/jcp.28086

Ejemplares similares

STAT3 and NF-κB cooperatively control in vitro spontaneous apoptosis and poor chemo-responsiveness in patients with chronic lymphocytic leukemia
por: Liu, Feng-Ting, et al.
Publicado: (2016)

Highly Sensitive and Accurate Assessment of Minimal Residual Disease in Chronic Lymphocytic Leukemia Using the Novel CD160-ROR1 Assay
por: Farren, Timothy W., et al.
Publicado: (2020)

Autocrine stimulation of interleukin 1 beta in acute myelogenous leukemia cells
Publicado: (1987)

T-cell dysfunction by pseudohypoxia and autocrine purinergic signaling in chronic lymphocytic leukemia
por: Montironi, Chiara, et al.
Publicado: (2023)

Multiple myeloma-derived Jagged ligands increases autocrine and paracrine interleukin-6 expression in bone marrow niche
por: Colombo, Michela, et al.
Publicado: (2016)

P593: T-CELL DYSFUNCTION BY PSEUDOHYPOXIA AND AUTOCRINE PURINERGIC SIGNALING IN CHRONIC LYMPHOCYTIC LEUKEMIA
por: Montironi, Chiara, et al.
Publicado: (2023)

Autocrine activin A signalling in ovarian cancer cells regulates secretion of interleukin 6, autophagy, and cachexia
por: Pettersen, Kristine, et al.
Publicado: (2019)

Global Transcriptional Profiling Reveals Novel Autocrine Functions of Interleukin 6 in Human Vascular Endothelial Cells
por: Ljungberg, Liza U., et al.
Publicado: (2020)

Interleukin 2 exerts autocrine stimulation on murine T-cell leukaemia growth.
por: Waldner, C. I., et al.
Publicado: (1997)

Interleukin-19 Acts as a Negative Autocrine Regulator of Activated Microglia
por: Horiuchi, Hiroshi, et al.
Publicado: (2015)

Revisiting the role of interleukin-8 in chronic lymphocytic leukemia
por: Risnik, Denise, et al.
Publicado: (2017)

Interleukin-27 tackles immunosuppression in chronic lymphocytic leukemia
por: Fernandez Botana, Iria, et al.
Publicado: (2023)

Regulation of T cell autocrine growth. T4+ cells become refractory to interleukin 2
Publicado: (1986)

Minimal residual disease detection with tumor-specific CD160 correlates with event-free survival in chronic lymphocytic leukemia
por: Farren, T W, et al.
Publicado: (2015)

Clinicopathological significance of overexpression of interleukin-6 in colorectal cancer
por: Zeng, Jun, et al.
Publicado: (2017)

Autocrine activation of the MET receptor tyrosine kinase in acute myeloid leukemia
por: Kentsis, Alex, et al.
Publicado: (2012)

Evaluation the -174G>C Genetic Polymorphism of Interleukin-6 in Iranian Patients with Chronic Lymphocytic Leukemia
por: Rostamzadeh Khameneh, Zakieh, et al.
Publicado: (2023)

Significance of serglycin and its binding partners in autocrine promotion of metastasis in esophageal cancer
por: Zhu, Yun, et al.
Publicado: (2021)

Significance of PPARA as a Treatment Target for Chronic Lymphocytic Leukemia
por: Xiang, Xixi, et al.
Publicado: (2023)

Autocrine Production of Interleukin-34 Promotes the Development of Endometriosis through CSF1R/JAK3/STAT6 signaling
por: Lin, Kaiqing, et al.
Publicado: (2019)

Autocrine IL-6 mediates pituitary tumor senescence
por: Sapochnik, Melanie, et al.
Publicado: (2016)

Obese cardiogenic arrest survivors with significant coronary artery disease had worse in-hospital mortality and neurological outcomes
por: Sung, Chih-Wei, et al.
Publicado: (2020)

Higher Platelet-to-Lymphocyte Ratio Is Associated With Worse Outcomes After Intravenous Thrombolysis in Acute Ischaemic Stroke
por: Xu, Jing-Han, et al.
Publicado: (2019)

Maintenance of Stemness in Oxaliplatin-Resistant Hepatocellular Carcinoma Is Associated with Increased Autocrine of IGF1
por: Bu, Yang, et al.
Publicado: (2014)

Higher autocrine motility factor/glucose-6-phosphate isomerase expression is associated with tumorigenesis and poorer prognosis in gastric cancer
por: Ma, Yu-Teng, et al.
Publicado: (2018)

Autocrine insulin-like growth factor 1 and stem cell factor but not interleukin 6 support self-renewal of human myeloma cells
por: Chiron, D, et al.
Publicado: (2013)

Interleukin-4 enhances proliferation of human pancreatic cancer cells: evidence for autocrine and paracrine actions
por: Prokopchuk, O, et al.
Publicado: (2005)

Autocrine growth and tumorigenicity of interleukin 2-dependent helper T cells transfected with IL-2 gene
Publicado: (1989)

Significance of Interleukin-6 in Papillary Thyroid Carcinoma
por: Kobawala, Toral P., et al.
Publicado: (2016)

CD2-mediated autocrine growth of herpes virus saimiri-transformed human T lymphocytes
Publicado: (1992)

Interleukin-27 and interleukin-35 in de novo acute myeloid leukemia: expression and significance as biological markers
por: Ahmed, Heba A, et al.
Publicado: (2019)

Chronic myeloid leukemia-derived exosomes promote tumor growth through an autocrine mechanism
por: Raimondo, Stefania, et al.
Publicado: (2015)

Autocrine interleukin-23 promotes self-renewal of CD133(+) ovarian cancer stem-like cells
por: Wang, Dan, et al.
Publicado: (2016)

Interleukin (IL)-9 Supports the Tumor-Promoting Environment of Chronic Lymphocytic Leukemia
por: Patrussi, Laura, et al.
Publicado: (2021)

Musashi-1 regulates AKT-derived IL-6 autocrinal/paracrinal malignancy and chemoresistance in glioblastoma
por: Chen, Hsiao-Yun, et al.
Publicado: (2016)

Activation of Vitamin D Regulates Response of Human Bronchial Epithelial Cells to Aspergillus fumigatus in an Autocrine Fashion
por: Li, Pei, et al.
Publicado: (2015)

Increased Plasma Cells and Decreased B-cells in Tumor Infiltrating Lymphocytes are Associated with Worse Survival in Lung Adenocarcinomas
por: Lee, Hee Eun, et al.
Publicado: (2020)

Interleukin 4 induces selective production of interleukin 6 from normal human B lymphocytes
Publicado: (1989)

Autocrine effects of PCSK9 on cardiomyocytes
por: Wolf, Annemarie, et al.
Publicado: (2020)

Interleukin-6 and interleukin-6 receptor secretion by chronic lymphatic leukaemia and normal B lymphocytes: effect of PMA and PWM
por: Drucker, I., et al.
Publicado: (1997)

Cannot write session to /tmp/vufind_sessions/sess_oitqufvakt6mj1100otm0gajjs