Identification of risk in cutaneous melanoma patients: Prognostic and predictive markers

New therapeutic modalities for melanoma promise benefit in selected individuals. Efficacy appears greater in patients with lower tumor burden, suggesting an important role for risk‐stratified surveillance. Robust predictive markers might permit optimization of agent to patient, while low‐risk progno...

Descripción completa

Detalles Bibliográficos
Autores principales: Hyams, David M., Cook, Robert W., Buzaid, Antonio C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Review Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6590387/
https://www.ncbi.nlm.nih.gov/pubmed/30548543
http://dx.doi.org/10.1002/jso.25319
_version_ 1783429548050743296
author Hyams, David M.
Cook, Robert W.
Buzaid, Antonio C.
author_facet Hyams, David M.
Cook, Robert W.
Buzaid, Antonio C.
author_sort Hyams, David M.
collection PubMed
description New therapeutic modalities for melanoma promise benefit in selected individuals. Efficacy appears greater in patients with lower tumor burden, suggesting an important role for risk‐stratified surveillance. Robust predictive markers might permit optimization of agent to patient, while low‐risk prognostic markers might guide more conservative management. This review evaluates protein, gene, and multiplexed marker panels that may contribute to better risk assessment and improved management of patients with cutaneous melanoma.
format Online
Article
Text
id pubmed-6590387
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher John Wiley and Sons Inc.
record_format MEDLINE/PubMed
spelling pubmed-65903872019-07-08 Identification of risk in cutaneous melanoma patients: Prognostic and predictive markers Hyams, David M. Cook, Robert W. Buzaid, Antonio C. J Surg Oncol Review Articles New therapeutic modalities for melanoma promise benefit in selected individuals. Efficacy appears greater in patients with lower tumor burden, suggesting an important role for risk‐stratified surveillance. Robust predictive markers might permit optimization of agent to patient, while low‐risk prognostic markers might guide more conservative management. This review evaluates protein, gene, and multiplexed marker panels that may contribute to better risk assessment and improved management of patients with cutaneous melanoma. John Wiley and Sons Inc. 2018-12-12 2019-02-01 /pmc/articles/PMC6590387/ /pubmed/30548543 http://dx.doi.org/10.1002/jso.25319 Text en © 2018 The Authors. Journal of Surgical Oncology Published by Wiley Periodicals, Inc. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Review Articles
Hyams, David M.
Cook, Robert W.
Buzaid, Antonio C.
Identification of risk in cutaneous melanoma patients: Prognostic and predictive markers
title Identification of risk in cutaneous melanoma patients: Prognostic and predictive markers
title_full Identification of risk in cutaneous melanoma patients: Prognostic and predictive markers
title_fullStr Identification of risk in cutaneous melanoma patients: Prognostic and predictive markers
title_full_unstemmed Identification of risk in cutaneous melanoma patients: Prognostic and predictive markers
title_short Identification of risk in cutaneous melanoma patients: Prognostic and predictive markers
title_sort identification of risk in cutaneous melanoma patients: prognostic and predictive markers
topic Review Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6590387/
https://www.ncbi.nlm.nih.gov/pubmed/30548543
http://dx.doi.org/10.1002/jso.25319
work_keys_str_mv AT hyamsdavidm identificationofriskincutaneousmelanomapatientsprognosticandpredictivemarkers
AT cookrobertw identificationofriskincutaneousmelanomapatientsprognosticandpredictivemarkers
AT buzaidantonioc identificationofriskincutaneousmelanomapatientsprognosticandpredictivemarkers

Ejemplares similares