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Feasibility of indocyanine green fluorescence imaging for intraoperative identification of parathyroid glands during thyroid surgery

BACKGROUND: This study assessed the feasibility of near‐infrared fluorescence imaging with indocyanine green (ICG) to identify the parathyroid glands (PGs) intraoperatively and to assess their perfusion after thyroid resection. METHODS: Patients undergoing elective thyroidectomy were enrolled in thi...

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Autores principales: van den Bos, Jacqueline, van Kooten, Lottie, Engelen, Sanne M. E., Lubbers, Tim, Stassen, Laurents P. S., Bouvy, Nicole D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6590433/
https://www.ncbi.nlm.nih.gov/pubmed/30536963
http://dx.doi.org/10.1002/hed.25451
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author van den Bos, Jacqueline
van Kooten, Lottie
Engelen, Sanne M. E.
Lubbers, Tim
Stassen, Laurents P. S.
Bouvy, Nicole D.
author_facet van den Bos, Jacqueline
van Kooten, Lottie
Engelen, Sanne M. E.
Lubbers, Tim
Stassen, Laurents P. S.
Bouvy, Nicole D.
author_sort van den Bos, Jacqueline
collection PubMed
description BACKGROUND: This study assessed the feasibility of near‐infrared fluorescence imaging with indocyanine green (ICG) to identify the parathyroid glands (PGs) intraoperatively and to assess their perfusion after thyroid resection. METHODS: Patients undergoing elective thyroidectomy were enrolled in this prospective study. An intravenous bolus of 7.5 mg ICG was administered twice: the first bolus to identify the PGs before resection of the thyroid and the second to assess vascularization of the PGs after resection. RESULTS: A total of 30 operations in 26 patients were included. In 17 surgeries (56.7%), fluorescence imaging was of added value, especially to confirm the presence of a suspected PG. No intraoperative or postoperative complications occurred because of the use of ICG. CONCLUSION: Near‐infrared fluorescence imaging with the use of ICG for intraoperative identification of the PGs and the assessment of its vascularization is feasible and safe and can provide more certainty about the location of the PGs.
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spelling pubmed-65904332019-07-08 Feasibility of indocyanine green fluorescence imaging for intraoperative identification of parathyroid glands during thyroid surgery van den Bos, Jacqueline van Kooten, Lottie Engelen, Sanne M. E. Lubbers, Tim Stassen, Laurents P. S. Bouvy, Nicole D. Head Neck Original Articles BACKGROUND: This study assessed the feasibility of near‐infrared fluorescence imaging with indocyanine green (ICG) to identify the parathyroid glands (PGs) intraoperatively and to assess their perfusion after thyroid resection. METHODS: Patients undergoing elective thyroidectomy were enrolled in this prospective study. An intravenous bolus of 7.5 mg ICG was administered twice: the first bolus to identify the PGs before resection of the thyroid and the second to assess vascularization of the PGs after resection. RESULTS: A total of 30 operations in 26 patients were included. In 17 surgeries (56.7%), fluorescence imaging was of added value, especially to confirm the presence of a suspected PG. No intraoperative or postoperative complications occurred because of the use of ICG. CONCLUSION: Near‐infrared fluorescence imaging with the use of ICG for intraoperative identification of the PGs and the assessment of its vascularization is feasible and safe and can provide more certainty about the location of the PGs. John Wiley & Sons, Inc. 2018-12-11 2019-02 /pmc/articles/PMC6590433/ /pubmed/30536963 http://dx.doi.org/10.1002/hed.25451 Text en © 2018 The Authors. Head & Neck published by Wiley Periodicals, Inc. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Articles
van den Bos, Jacqueline
van Kooten, Lottie
Engelen, Sanne M. E.
Lubbers, Tim
Stassen, Laurents P. S.
Bouvy, Nicole D.
Feasibility of indocyanine green fluorescence imaging for intraoperative identification of parathyroid glands during thyroid surgery
title Feasibility of indocyanine green fluorescence imaging for intraoperative identification of parathyroid glands during thyroid surgery
title_full Feasibility of indocyanine green fluorescence imaging for intraoperative identification of parathyroid glands during thyroid surgery
title_fullStr Feasibility of indocyanine green fluorescence imaging for intraoperative identification of parathyroid glands during thyroid surgery
title_full_unstemmed Feasibility of indocyanine green fluorescence imaging for intraoperative identification of parathyroid glands during thyroid surgery
title_short Feasibility of indocyanine green fluorescence imaging for intraoperative identification of parathyroid glands during thyroid surgery
title_sort feasibility of indocyanine green fluorescence imaging for intraoperative identification of parathyroid glands during thyroid surgery
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6590433/
https://www.ncbi.nlm.nih.gov/pubmed/30536963
http://dx.doi.org/10.1002/hed.25451
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