Modeling and multiscale characterization of the quantitative imaging based fibrosis index reveals pathophysiological, transcriptome and proteomic correlates of lung fibrosis induced by fractionated irradiation

Pulmonary fibrosis represents a leading cause of morbidity and mortality worldwide. Therapy induced lung fibrosis constitutes a pivotal dose‐limiting side effect of radiotherapy and other anticancer agents. We aimed to develop objective criteria for assessment of fibrosis and discover pathophysiolog...

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Detalles Bibliográficos
Autores principales: Zhou, Cheng, Moustafa, Mahmoud R., Cao, Liji, Kriegsmann, Mark, Winter, Martin, Schwager, Christian, Jones, Bleddyn, Wang, Shijun, Bäuerle, Tobias, Zhou, Ping‐Kun, Schnölzer, Martina, Weichert, Wilko, Debus, Juergen, Abdollahi, Amir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2019
Materias:
Cancer Therapy and Prevention
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6590477/
https://www.ncbi.nlm.nih.gov/pubmed/30536712
http://dx.doi.org/10.1002/ijc.32059

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6590477/
https://www.ncbi.nlm.nih.gov/pubmed/30536712
http://dx.doi.org/10.1002/ijc.32059

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