Desensitization of cAMP Accumulation via Human β3-Adrenoceptors Expressed in Human Embryonic Kidney Cells by Full, Partial, and Biased Agonists

β(3)-Adrenoceptors couple not only to cAMP formation but, at least in some cell types, also to alternative signaling pathways such as phosphorylation of extracellular signal-regulated kinase (ERK). β(3)-Adrenoceptor agonists are used in long-term symptomatic treatment of the overactive bladder syndr...

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Detalles Bibliográficos
Autores principales: Okeke, Katerina, Michel-Reher, Martina B., Gravas, Stavros, Michel, Martin C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6590479/
https://www.ncbi.nlm.nih.gov/pubmed/31263412
http://dx.doi.org/10.3389/fphar.2019.00596

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6590479/
https://www.ncbi.nlm.nih.gov/pubmed/31263412
http://dx.doi.org/10.3389/fphar.2019.00596

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