Cargando…
HIF‐1α/VEGF signaling‐mediated epithelial–mesenchymal transition and angiogenesis is critically involved in anti‐metastasis effect of luteolin in melanoma cells
Tumor metastasis is still the leading cause of melanoma mortality. Luteolin, a natural flavonoid, is found in fruits, vegetables, and medicinal herbs. The pharmacological action and mechanism of luteolin on the metastasis of melanoma remain elusive. In this study, we investigated the effect of luteo...
Autores principales: | Li, Chunyu, Wang, Qi, Shen, Shen, Wei, Xiaolu, Li, Guoxia |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6590488/ https://www.ncbi.nlm.nih.gov/pubmed/30653763 http://dx.doi.org/10.1002/ptr.6273 |
Ejemplares similares
-
Oridonin inhibits VEGF-A-associated angiogenesis and epithelial-mesenchymal transition of breast cancer in vitro and in vivo
por: Li, Chunyu, et al.
Publicado: (2018) -
Regulation of Osteogenesis-Angiogenesis Coupling by HIFs and VEGF
por: Schipani, Ernestina, et al.
Publicado: (2009) -
LRG1 modulates epithelial-mesenchymal transition and angiogenesis in colorectal cancer via HIF-1α activation
por: Zhang, Jingjing, et al.
Publicado: (2016) -
Tetrahydrocurcumin induces mesenchymal-epithelial transition and suppresses angiogenesis by targeting HIF-1α and autophagy in human osteosarcoma
por: Zhang, Yan, et al.
Publicado: (2017) -
Luteolin suppresses gastric cancer progression by reversing epithelial-mesenchymal transition via suppression of the Notch signaling pathway
por: Zang, Ming-de, et al.
Publicado: (2017)