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Autoimmune Hepatitis (AIH) in Acquired Immune Deficiency Syndrome (AIDS): A Case Report and Review of Literature

The common causes of abnormal liver chemistries in human immunodeficiency virus (HIV) infected patients are multifactorial. Diagnosis of autoimmune hepatitis (AIH) in HIV infected patients is intriguing but data is scarce. Unmasking of AIH during immune reconstitution in HIV patients after starting...

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Detalles Bibliográficos
Autores principales: Roussel, Jordan, Pandit, Sudha, Jordan, Paul, Boktor, Moheb, Knowles, Kurt, Dela Cruz, Nester, Samant, Hrishikesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6590560/
https://www.ncbi.nlm.nih.gov/pubmed/31281688
http://dx.doi.org/10.1155/2019/5326428
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author Roussel, Jordan
Pandit, Sudha
Jordan, Paul
Boktor, Moheb
Knowles, Kurt
Dela Cruz, Nester
Samant, Hrishikesh
author_facet Roussel, Jordan
Pandit, Sudha
Jordan, Paul
Boktor, Moheb
Knowles, Kurt
Dela Cruz, Nester
Samant, Hrishikesh
author_sort Roussel, Jordan
collection PubMed
description The common causes of abnormal liver chemistries in human immunodeficiency virus (HIV) infected patients are multifactorial. Diagnosis of autoimmune hepatitis (AIH) in HIV infected patients is intriguing but data is scarce. Unmasking of AIH during immune reconstitution in HIV patients after starting antiretroviral therapy is reported but not with advanced acquired immunodeficiency syndrome (AIDS). Here we present a fascinating case of 32-year-old African-American man with advanced AIDS who presented with elevated transaminases. He was diagnosed with AIH before starting antiretroviral therapy and successfully treated with prednisolone and azathioprine with antiretroviral therapy despite very low CD4 count.
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spelling pubmed-65905602019-07-07 Autoimmune Hepatitis (AIH) in Acquired Immune Deficiency Syndrome (AIDS): A Case Report and Review of Literature Roussel, Jordan Pandit, Sudha Jordan, Paul Boktor, Moheb Knowles, Kurt Dela Cruz, Nester Samant, Hrishikesh Case Reports Hepatol Case Report The common causes of abnormal liver chemistries in human immunodeficiency virus (HIV) infected patients are multifactorial. Diagnosis of autoimmune hepatitis (AIH) in HIV infected patients is intriguing but data is scarce. Unmasking of AIH during immune reconstitution in HIV patients after starting antiretroviral therapy is reported but not with advanced acquired immunodeficiency syndrome (AIDS). Here we present a fascinating case of 32-year-old African-American man with advanced AIDS who presented with elevated transaminases. He was diagnosed with AIH before starting antiretroviral therapy and successfully treated with prednisolone and azathioprine with antiretroviral therapy despite very low CD4 count. Hindawi 2019-06-09 /pmc/articles/PMC6590560/ /pubmed/31281688 http://dx.doi.org/10.1155/2019/5326428 Text en Copyright © 2019 Jordan Roussel et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Roussel, Jordan
Pandit, Sudha
Jordan, Paul
Boktor, Moheb
Knowles, Kurt
Dela Cruz, Nester
Samant, Hrishikesh
Autoimmune Hepatitis (AIH) in Acquired Immune Deficiency Syndrome (AIDS): A Case Report and Review of Literature
title Autoimmune Hepatitis (AIH) in Acquired Immune Deficiency Syndrome (AIDS): A Case Report and Review of Literature
title_full Autoimmune Hepatitis (AIH) in Acquired Immune Deficiency Syndrome (AIDS): A Case Report and Review of Literature
title_fullStr Autoimmune Hepatitis (AIH) in Acquired Immune Deficiency Syndrome (AIDS): A Case Report and Review of Literature
title_full_unstemmed Autoimmune Hepatitis (AIH) in Acquired Immune Deficiency Syndrome (AIDS): A Case Report and Review of Literature
title_short Autoimmune Hepatitis (AIH) in Acquired Immune Deficiency Syndrome (AIDS): A Case Report and Review of Literature
title_sort autoimmune hepatitis (aih) in acquired immune deficiency syndrome (aids): a case report and review of literature
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6590560/
https://www.ncbi.nlm.nih.gov/pubmed/31281688
http://dx.doi.org/10.1155/2019/5326428
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