Cargando…

−254C>G SNP in the TRPC6 Gene Promoter Influences Its Expression via Interaction with the NF-κB Subunit RELA in Steroid-Resistant Nephrotic Syndrome Children

This study is aimed at exploring the mechanism by which the −254C>G single nucleotide polymorphism (SNP) on the transient receptor potential cation channel 6 (TRPC6) gene promoter could increase its activation in steroid-resistant nephrotic syndrome children of China. Plasmids containing the TRPC...

Descripción completa

Detalles Bibliográficos
Autores principales: Kuang, Xinyu, Zhou, Qian, Li, Zhuying, Hu, Yujie, Kang, Yulin, Huang, Wenyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6590578/
https://www.ncbi.nlm.nih.gov/pubmed/31281825
http://dx.doi.org/10.1155/2019/2197837