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Low Bioelectrical Impedance Phase Angle Is a Significant Risk Factor for Frailty
The phase angle, which is measured via bioelectrical impedance analysis (BIA), is a clinically important bioimpedance parameter used for nutritional assessment and evaluating the risk of various diseases, such as locomotive syndrome (LS). It remains unclear if the phase angle is associated with frai...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6590642/ https://www.ncbi.nlm.nih.gov/pubmed/31281842 http://dx.doi.org/10.1155/2019/6283153 |
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author | Tanaka, Satoshi Ando, Kei Kobayashi, Kazuyoshi Seki, Taisuke Hamada, Takashi Machino, Masaaki Ota, Kyotaro Morozumi, Masayoshi Kanbara, Shunsuke Ito, Sadayuki Ishiguro, Naoki Hasegawa, Yukiharu Imagama, Shiro |
author_facet | Tanaka, Satoshi Ando, Kei Kobayashi, Kazuyoshi Seki, Taisuke Hamada, Takashi Machino, Masaaki Ota, Kyotaro Morozumi, Masayoshi Kanbara, Shunsuke Ito, Sadayuki Ishiguro, Naoki Hasegawa, Yukiharu Imagama, Shiro |
author_sort | Tanaka, Satoshi |
collection | PubMed |
description | The phase angle, which is measured via bioelectrical impedance analysis (BIA), is a clinically important bioimpedance parameter used for nutritional assessment and evaluating the risk of various diseases, such as locomotive syndrome (LS). It remains unclear if the phase angle is associated with frailty (fragile state of physical and mental health). We therefore examined this association in a large prospective sample. Of 1081 individuals receiving health checkups, 550 (male; 235, female; 365) were enrolled in this study. We applied the Japanese version of the Cardiovascular Health Study criteria to evaluate frailty and administered the 25-Item Geriatric Locomotive Function Scale to diagnose LS. The phase angle was measured via BIA. Multiple logistic regression analysis was used to evaluate the relationship between the phase angle and frailty. For all participants and for each sex, the phase angle was significantly lower among individuals with frailty. After controlling for age, sex, and body mass index, we found that a low phase angle was a significant risk factor of frailty. As a result of multiple regression analysis including other confounding factors, among male participants, a low phase angle was significantly related with both frailty (P = 0.015) and LS (P < 0.001), whereas among female participants, the low phase angle had a stronger association with frailty (P = 0.001) than with LS (P = 0.52). Our findings suggest that a low angle is a risk factor of frailty. Furthermore, among female participants, frailty has a stronger relation with the phase angle than does LS. Therefore, the phase angle may be considered a useful indicator of frailty that does not require lengthy or costly assessment. |
format | Online Article Text |
id | pubmed-6590642 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-65906422019-07-07 Low Bioelectrical Impedance Phase Angle Is a Significant Risk Factor for Frailty Tanaka, Satoshi Ando, Kei Kobayashi, Kazuyoshi Seki, Taisuke Hamada, Takashi Machino, Masaaki Ota, Kyotaro Morozumi, Masayoshi Kanbara, Shunsuke Ito, Sadayuki Ishiguro, Naoki Hasegawa, Yukiharu Imagama, Shiro Biomed Res Int Research Article The phase angle, which is measured via bioelectrical impedance analysis (BIA), is a clinically important bioimpedance parameter used for nutritional assessment and evaluating the risk of various diseases, such as locomotive syndrome (LS). It remains unclear if the phase angle is associated with frailty (fragile state of physical and mental health). We therefore examined this association in a large prospective sample. Of 1081 individuals receiving health checkups, 550 (male; 235, female; 365) were enrolled in this study. We applied the Japanese version of the Cardiovascular Health Study criteria to evaluate frailty and administered the 25-Item Geriatric Locomotive Function Scale to diagnose LS. The phase angle was measured via BIA. Multiple logistic regression analysis was used to evaluate the relationship between the phase angle and frailty. For all participants and for each sex, the phase angle was significantly lower among individuals with frailty. After controlling for age, sex, and body mass index, we found that a low phase angle was a significant risk factor of frailty. As a result of multiple regression analysis including other confounding factors, among male participants, a low phase angle was significantly related with both frailty (P = 0.015) and LS (P < 0.001), whereas among female participants, the low phase angle had a stronger association with frailty (P = 0.001) than with LS (P = 0.52). Our findings suggest that a low angle is a risk factor of frailty. Furthermore, among female participants, frailty has a stronger relation with the phase angle than does LS. Therefore, the phase angle may be considered a useful indicator of frailty that does not require lengthy or costly assessment. Hindawi 2019-06-10 /pmc/articles/PMC6590642/ /pubmed/31281842 http://dx.doi.org/10.1155/2019/6283153 Text en Copyright © 2019 Satoshi Tanaka et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Tanaka, Satoshi Ando, Kei Kobayashi, Kazuyoshi Seki, Taisuke Hamada, Takashi Machino, Masaaki Ota, Kyotaro Morozumi, Masayoshi Kanbara, Shunsuke Ito, Sadayuki Ishiguro, Naoki Hasegawa, Yukiharu Imagama, Shiro Low Bioelectrical Impedance Phase Angle Is a Significant Risk Factor for Frailty |
title | Low Bioelectrical Impedance Phase Angle Is a Significant Risk Factor for Frailty |
title_full | Low Bioelectrical Impedance Phase Angle Is a Significant Risk Factor for Frailty |
title_fullStr | Low Bioelectrical Impedance Phase Angle Is a Significant Risk Factor for Frailty |
title_full_unstemmed | Low Bioelectrical Impedance Phase Angle Is a Significant Risk Factor for Frailty |
title_short | Low Bioelectrical Impedance Phase Angle Is a Significant Risk Factor for Frailty |
title_sort | low bioelectrical impedance phase angle is a significant risk factor for frailty |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6590642/ https://www.ncbi.nlm.nih.gov/pubmed/31281842 http://dx.doi.org/10.1155/2019/6283153 |
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