Putative Role of Nuclear Factor-Kappa B But Not Hypoxia-Inducible Factor-1α in Hypoxia-Dependent Regulation of Oxidative Stress in Hematopoietic Stem and Progenitor Cells

Aims: Adaptation to low oxygen of hematopoietic stem cells (HSCs) in the bone marrow has been demonstrated to depend on the activation of hypoxia-inducible factor (HIF)-1α as well as the limited production of reactive oxygen species (ROS). In this study, we aimed at determining whether HIF-1α is inv...

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Detalles Bibliográficos
Autores principales: Halvarsson, Camilla, Rörby, Emma, Eliasson, Pernilla, Lang, Stefan, Soneji, Shamit, Jönsson, Jan-Ingvar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2019
Materias:
Original Research Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6590716/
https://www.ncbi.nlm.nih.gov/pubmed/30827134
http://dx.doi.org/10.1089/ars.2018.7551

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