Diagnosis of Chagasic Encephalitis by Sequencing of 28S rRNA Gene

We report a case of chagasic encephalitis diagnosed by 28S rRNA sequencing. The diagnosis of chagasic encephalitis is challenging, given the broad differential diagnosis for central nervous system lesions in immunocompromised patients and low sensitivity of traditional diagnostics. Sequencing should...

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Detalles Bibliográficos
Autores principales: Multani, Ashrit, Meer, Aabed, Smith, Darvin S., Kheraj, Malika N., Plowey, Edward D., Blackburn, Brian G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2019
Materias:
Dispatch
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6590746/
https://www.ncbi.nlm.nih.gov/pubmed/31211674
http://dx.doi.org/10.3201/eid2507.180285
Descripción
Sumario:We report a case of chagasic encephalitis diagnosed by 28S rRNA sequencing. The diagnosis of chagasic encephalitis is challenging, given the broad differential diagnosis for central nervous system lesions in immunocompromised patients and low sensitivity of traditional diagnostics. Sequencing should be part of the diagnostic armamentarium for potential chagasic encephalitis.

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