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Adenovirus-mediated expression of SIK1 improves hepatic glucose and lipid metabolism in type 2 diabetes mellitus rats

AIM: In this study, we investigated the role and mechanism of Salt-induced kinase 1 (SIK1) in regulation of hepatic glucose and lipid metabolism in a high-fat food (HFD) and streptozocin (STZ)-induced type 2 diabetes mellitus (T2DM) rat model. METHODS: A diabetic rat model treated with HFD plus low-...

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Detalles Bibliográficos
Autores principales:	Song, DaoFei, Yin, Lei, Wang, Chang, Wen, XiuYing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6590778/ https://www.ncbi.nlm.nih.gov/pubmed/31233505 http://dx.doi.org/10.1371/journal.pone.0210930

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