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Screening of urine identifies PLA2G16 as a field defect methylation biomarker for prostate cancer detection
BACKGROUND: Prostate cancer (PC) is a multifocal disease. DNA methylation alterations are not restricted to the immediate peritumor environment, but spatially widespread in the adjacent and distant histologically normal prostate tissues. In the current study, we utilized high-throughput methylation...
Autores principales: | Jarrard, William E., Schultz, Adam, Etheridge, Tyler, Damodaran, Shivashankar, Allen, Glenn O., Jarrard, David, Yang, Bing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6590820/ https://www.ncbi.nlm.nih.gov/pubmed/31233548 http://dx.doi.org/10.1371/journal.pone.0218950 |
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