Sera Antibody Repertoire Analyses Reveal Mechanisms of Broad and Pandemic Strain Neutralizing Responses after Human Norovirus Vaccination

Rapidly evolving RNA viruses, such as the GII.4 strain of human norovirus (HuNoV), and their vaccines elicit complex serological responses associated with previous exposure. Specific correlates of protection, moreover, remain poorly understood. Here, we report the GII.4-serological antibody repertoi...

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Detalles Bibliográficos
Autores principales: Lindesmith, Lisa C., McDaniel, Jonathan R., Changela, Anita, Verardi, Raffaello, Kerr, Scott A., Costantini, Veronica, Brewer-Jensen, Paul D., Mallory, Michael L., Voss, William N., Boutz, Daniel R., Blazeck, John J., Ippolito, Gregory C., Vinje, Jan, Kwong, Peter D., Georgiou, George, Baric, Ralph S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591005/
https://www.ncbi.nlm.nih.gov/pubmed/31216462
http://dx.doi.org/10.1016/j.immuni.2019.05.007

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