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Investigating the properties of TBA variants with twin thrombin binding domains

In this paper, we report studies concerning thrombin binding aptamer (TBA) dimeric derivatives in which the 3′-ends of two TBA sequences have been joined by means of linkers containing adenosine or thymidine residues and/or a glycerol moiety. CD and electrophoretic investigations indicate that all m...

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Detalles Bibliográficos
Autores principales: Amato, Teresa, Virgilio, Antonella, Pirone, Luciano, Vellecco, Valentina, Bucci, Mariarosaria, Pedone, Emilia, Esposito, Veronica, Galeone, Aldo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591170/
https://www.ncbi.nlm.nih.gov/pubmed/31235717
http://dx.doi.org/10.1038/s41598-019-45526-z