The analysis of clinical and laboratory data: a large outbreak of dengue fever in Chaozhou, Guangdong province, China

A large-scale dengue fever (DF) outbreak occurred in Chaozhou, Guangdong province, China 2015. In our study, 528 dengue-positive patient samples were collected for clinical and laboratory data analysis. 491 cases (93.0%) were primary dengue fever (PDF), 22 cases (4.2%) were dengue hemorrhagic fever...

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Autores principales: Lin, Fen, Yang, Hui, Zhang, Lin, Fang, Sen-Hai, Zhan, Xiao-Fen, Yang, Li-Ye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2019
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591201/
https://www.ncbi.nlm.nih.gov/pubmed/31102050
http://dx.doi.org/10.1007/s00705-019-04266-1
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author Lin, Fen
Yang, Hui
Zhang, Lin
Fang, Sen-Hai
Zhan, Xiao-Fen
Yang, Li-Ye
author_facet Lin, Fen
Yang, Hui
Zhang, Lin
Fang, Sen-Hai
Zhan, Xiao-Fen
Yang, Li-Ye
author_sort Lin, Fen
collection PubMed
description A large-scale dengue fever (DF) outbreak occurred in Chaozhou, Guangdong province, China 2015. In our study, 528 dengue-positive patient samples were collected for clinical and laboratory data analysis. 491 cases (93.0%) were primary dengue fever (PDF), 22 cases (4.2%) were dengue hemorrhagic fever (DHF) and 15 cases (2.8%) were diagnosed with severe dengue fever (SDF). All cases were infected by dengue virus serotype 2 (DENV-2), and the isolated strains belonged to cosmopolitan genotype, which were grouped closely with Malaysia strains from 2010 to 2014. Moreover, the study showed that laboratory indices have significantly difference in PDF, DHF and SDF patients. A comprehensive analysis of these data could assist and guide the clinical diagnosis for DF, which has an important significance for the control of dengue virus infection.
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spelling pubmed-65912012019-07-11 The analysis of clinical and laboratory data: a large outbreak of dengue fever in Chaozhou, Guangdong province, China Lin, Fen Yang, Hui Zhang, Lin Fang, Sen-Hai Zhan, Xiao-Fen Yang, Li-Ye Arch Virol Brief Report A large-scale dengue fever (DF) outbreak occurred in Chaozhou, Guangdong province, China 2015. In our study, 528 dengue-positive patient samples were collected for clinical and laboratory data analysis. 491 cases (93.0%) were primary dengue fever (PDF), 22 cases (4.2%) were dengue hemorrhagic fever (DHF) and 15 cases (2.8%) were diagnosed with severe dengue fever (SDF). All cases were infected by dengue virus serotype 2 (DENV-2), and the isolated strains belonged to cosmopolitan genotype, which were grouped closely with Malaysia strains from 2010 to 2014. Moreover, the study showed that laboratory indices have significantly difference in PDF, DHF and SDF patients. A comprehensive analysis of these data could assist and guide the clinical diagnosis for DF, which has an important significance for the control of dengue virus infection. Springer Vienna 2019-05-17 2019 /pmc/articles/PMC6591201/ /pubmed/31102050 http://dx.doi.org/10.1007/s00705-019-04266-1 Text en © The Author(s) 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Brief Report
Lin, Fen
Yang, Hui
Zhang, Lin
Fang, Sen-Hai
Zhan, Xiao-Fen
Yang, Li-Ye
The analysis of clinical and laboratory data: a large outbreak of dengue fever in Chaozhou, Guangdong province, China
title The analysis of clinical and laboratory data: a large outbreak of dengue fever in Chaozhou, Guangdong province, China
title_full The analysis of clinical and laboratory data: a large outbreak of dengue fever in Chaozhou, Guangdong province, China
title_fullStr The analysis of clinical and laboratory data: a large outbreak of dengue fever in Chaozhou, Guangdong province, China
title_full_unstemmed The analysis of clinical and laboratory data: a large outbreak of dengue fever in Chaozhou, Guangdong province, China
title_short The analysis of clinical and laboratory data: a large outbreak of dengue fever in Chaozhou, Guangdong province, China
title_sort analysis of clinical and laboratory data: a large outbreak of dengue fever in chaozhou, guangdong province, china
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591201/
https://www.ncbi.nlm.nih.gov/pubmed/31102050
http://dx.doi.org/10.1007/s00705-019-04266-1
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