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Transcriptome Analysis of Long-lived Drosophila melanogaster E(z) Mutants Sheds Light on the Molecular Mechanisms of Longevity

The E(z) histone methyltransferase heterozygous mutation in Drosophila is known to increase lifespan and stress resistance. However, the longevity mechanisms of E(z) mutants have not been revealed. Using genome-wide transcriptome analysis, we demonstrated that lifespan extension, increase of resista...

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Detalles Bibliográficos
Autores principales:	Moskalev, Alexey A., Shaposhnikov, Mikhail V., Zemskaya, Nadezhda V., Koval, Liubov А., Schegoleva, Eugenia V., Guvatova, Zulfiya G., Krasnov, George S., Solovev, Ilya A., Sheptyakov, Maksim A., Zhavoronkov, Alex, Kudryavtseva, Anna V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591219/ https://www.ncbi.nlm.nih.gov/pubmed/31235842 http://dx.doi.org/10.1038/s41598-019-45714-x

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