QSAR Classification Models for Predicting the Activity of Inhibitors of Beta-Secretase (BACE1) Associated with Alzheimer’s Disease

Alzheimer’s disease is one of the most common neurodegenerative disorders in elder population. The β-site amyloid cleavage enzyme 1 (BACE1) is the major constituent of amyloid plaques and plays a central role in this brain pathogenesis, thus it constitutes an auspicious pharmacological target for it...

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Detalles Bibliográficos
Autores principales: Ponzoni, Ignacio, Sebastián-Pérez, Víctor, Martínez, María J., Roca, Carlos, De la Cruz Pérez, Carlos, Cravero, Fiorella, Vazquez, Gustavo E., Páez, Juan A., Díaz, Mónica F., Campillo, Nuria E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591229/
https://www.ncbi.nlm.nih.gov/pubmed/31235739
http://dx.doi.org/10.1038/s41598-019-45522-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591229/
https://www.ncbi.nlm.nih.gov/pubmed/31235739
http://dx.doi.org/10.1038/s41598-019-45522-3

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