Chromosome dynamics near the sol-gel phase transition dictate the timing of remote genomic interactions

Diverse antibody repertoires are generated through remote genomic interactions involving immunoglobulin variable (V(H)), diversity (D(H)) and joining (J(H)) gene segments. How such interactions are orchestrated remains unknown. Here we develop a strategy to track V(H)-D(H)J(H) motion in B-lymphocyte...

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Detalles Bibliográficos
Autores principales: Khanna, Nimish, Zhang, Yaojun, Lucas, Joseph S., Dudko, Olga K., Murre, Cornelis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591236/
https://www.ncbi.nlm.nih.gov/pubmed/31235807
http://dx.doi.org/10.1038/s41467-019-10628-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591236/
https://www.ncbi.nlm.nih.gov/pubmed/31235807
http://dx.doi.org/10.1038/s41467-019-10628-9

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