Cargando…
Protective effects of the Francisella tularensis ΔpdpC mutant against its virulent parental strain SCHU P9 in Cynomolgus macaques
Tularemia is a severe infectious zoonotic disease caused by Francisella tularensis. Although F. tularensis is considered to be a potential biological weapon due to its high infectivity and mortality rate, no vaccine has been currently licensed. Recently, we reported that F. tularensis SCHU P9 derive...
Autores principales: | Tian, Deyu, Uda, Akihiko, Ami, Yasushi, Hotta, Akitoyo, Park, Eun-sil, Nagata, Noriyo, Iwata-Yoshikawa, Naoko, Yamada, Akio, Hirayama, Kazuhiro, Miura, Kozue, Koyama, Yuki, Azaki, Mika, Morikawa, Shigeru |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591246/ https://www.ncbi.nlm.nih.gov/pubmed/31235714 http://dx.doi.org/10.1038/s41598-019-45412-8 |
Ejemplares similares
-
Role of Pathogenicity Determinant Protein C (PdpC) in Determining the Virulence of the Francisella tularensis Subspecies tularensis SCHU
por: Uda, Akihiko, et al.
Publicado: (2014) -
Effective methods for the inactivation of Francisella tularensis
por: Azaki, Mika, et al.
Publicado: (2019) -
Pullulanase Is Necessary for the Efficient Intracellular Growth of Francisella tularensis
por: Uda, Akihiko, et al.
Publicado: (2016) -
The Francisella tularensis LVS ΔpdpC mutant exhibits a unique phenotype during intracellular infection
por: Lindgren, Marie, et al.
Publicado: (2013) -
PdpC, a secreted effector protein of the type six secretion system, is required for erythrocyte invasion by Francisella tularensis LVS
por: Cantlay, Stuart, et al.
Publicado: (2022)