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Midostaurin Reverses ABCB1-Mediated Multidrug Resistance, an in vitro Study

Overexpression of ABC transporters in cancer cells is an underlying mechanism of multidrug resistance (MDR), leading to insensitive response to chemotherapeutic strategies. Thus, MDR is often results in treatment failure in the clinic. In this study, we found midostaurin, a Food and Drug Administrat...

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Detalles Bibliográficos
Autores principales:	Ji, Ning, Yang, Yuqi, Cai, Chao-Yun, Wang, Jing-Quan, Lei, Zi-Ning, Wu, Zhuo-Xun, Cui, Qingbin, Yang, Dong-Hua, Chen, Zhe-Sheng, Kong, Dexin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591272/ https://www.ncbi.nlm.nih.gov/pubmed/31275850 http://dx.doi.org/10.3389/fonc.2019.00514

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