Gliotoxin Induces Cofilin Phosphorylation to Promote Actin Cytoskeleton Dynamics and Internalization of Aspergillus fumigatus Into Type II Human Pneumocyte Cells

Aspergillus fumigatus is able to internalize into lung epithelial cells to escape from immune attack for further dissemination. We previously reported that gliotoxin, a major mycotoxin of A. fumigatus, promotes this internalization; however, the mechanism remained unclear. Here, we report that gliot...

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Detalles Bibliográficos
Autores principales: Zhang, Changjian, Chen, Fangyan, Liu, Xiaoyu, Han, Xuelin, Hu, Yingsong, Su, Xueting, Chen, Yong, Sun, Yansong, Han, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591310/
https://www.ncbi.nlm.nih.gov/pubmed/31275272
http://dx.doi.org/10.3389/fmicb.2019.01345

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