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Beyond Arabidopsis: Differential UV-B Response Mediated by UVR8 in Diverse Species

Ultraviolet-B radiation (UV-B, 280–315 nm) is an important environmental signal that regulates growth and development in plants. Two dose-dependent UV-B response pathways were described in plants: a specific one, mediated by UVR8 (the specific UV-B receptor) and an unspecific one, activated by the o...

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Autores principales: Tossi, Vanesa Eleonora, Regalado, Jose Javier, Iannicelli, Jesica, Laino, Leandro Ezequiel, Burrieza, Hernan Pablo, Escandón, Alejandro Salvio, Pitta-Álvarez, Sandra Irene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591365/
https://www.ncbi.nlm.nih.gov/pubmed/31275337
http://dx.doi.org/10.3389/fpls.2019.00780
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author Tossi, Vanesa Eleonora
Regalado, Jose Javier
Iannicelli, Jesica
Laino, Leandro Ezequiel
Burrieza, Hernan Pablo
Escandón, Alejandro Salvio
Pitta-Álvarez, Sandra Irene
author_facet Tossi, Vanesa Eleonora
Regalado, Jose Javier
Iannicelli, Jesica
Laino, Leandro Ezequiel
Burrieza, Hernan Pablo
Escandón, Alejandro Salvio
Pitta-Álvarez, Sandra Irene
author_sort Tossi, Vanesa Eleonora
collection PubMed
description Ultraviolet-B radiation (UV-B, 280–315 nm) is an important environmental signal that regulates growth and development in plants. Two dose-dependent UV-B response pathways were described in plants: a specific one, mediated by UVR8 (the specific UV-B receptor) and an unspecific one, activated by the oxidative damage produced by radiation. The constitutively expressed receptor appears inactive as a dimer, with the two monomers dissociating upon UV-B irradiation. The monomer then interacts with COP1, an ubiquitin ligase, hindering its ability to poly-ubiquitinate transcriptional factor HY5, thus averting its degradation and activating the photomorphogenic response. HY5 induces the synthesis of proteins RUP1 and RUP2, which interact with UVR8, releasing COP1, and inducing the re-dimerization of UVR8. This mechanism has been thoroughly characterized in Arabidopsis, where studies have demonstrated that the UVR8 receptor is key in UV-B response. Although Arabidopsis importance as a model plant many mechanisms described in this specie differ in other plants. In this paper, we review the latest information regarding UV-B response mediated by UVR8 in different species, focusing on the differences reported compared to Arabidopsis. For instance, UVR8 is not only induced by UV-B but also by other agents that are expressed differentially in diverse tissues. Also, in some of the species analyzed, proteins with low homology to RUP1 and RUP2 were detected. We also discuss how UVR8 is involved in other developmental and stress processes unrelated to UV-B. We conclude that the receptor is highly versatile, showing differences among species.
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spelling pubmed-65913652019-07-02 Beyond Arabidopsis: Differential UV-B Response Mediated by UVR8 in Diverse Species Tossi, Vanesa Eleonora Regalado, Jose Javier Iannicelli, Jesica Laino, Leandro Ezequiel Burrieza, Hernan Pablo Escandón, Alejandro Salvio Pitta-Álvarez, Sandra Irene Front Plant Sci Plant Science Ultraviolet-B radiation (UV-B, 280–315 nm) is an important environmental signal that regulates growth and development in plants. Two dose-dependent UV-B response pathways were described in plants: a specific one, mediated by UVR8 (the specific UV-B receptor) and an unspecific one, activated by the oxidative damage produced by radiation. The constitutively expressed receptor appears inactive as a dimer, with the two monomers dissociating upon UV-B irradiation. The monomer then interacts with COP1, an ubiquitin ligase, hindering its ability to poly-ubiquitinate transcriptional factor HY5, thus averting its degradation and activating the photomorphogenic response. HY5 induces the synthesis of proteins RUP1 and RUP2, which interact with UVR8, releasing COP1, and inducing the re-dimerization of UVR8. This mechanism has been thoroughly characterized in Arabidopsis, where studies have demonstrated that the UVR8 receptor is key in UV-B response. Although Arabidopsis importance as a model plant many mechanisms described in this specie differ in other plants. In this paper, we review the latest information regarding UV-B response mediated by UVR8 in different species, focusing on the differences reported compared to Arabidopsis. For instance, UVR8 is not only induced by UV-B but also by other agents that are expressed differentially in diverse tissues. Also, in some of the species analyzed, proteins with low homology to RUP1 and RUP2 were detected. We also discuss how UVR8 is involved in other developmental and stress processes unrelated to UV-B. We conclude that the receptor is highly versatile, showing differences among species. Frontiers Media S.A. 2019-06-18 /pmc/articles/PMC6591365/ /pubmed/31275337 http://dx.doi.org/10.3389/fpls.2019.00780 Text en Copyright © 2019 Tossi, Regalado, Iannicelli, Laino, Burrieza, Escandón and Pitta-Álvarez. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Plant Science
Tossi, Vanesa Eleonora
Regalado, Jose Javier
Iannicelli, Jesica
Laino, Leandro Ezequiel
Burrieza, Hernan Pablo
Escandón, Alejandro Salvio
Pitta-Álvarez, Sandra Irene
Beyond Arabidopsis: Differential UV-B Response Mediated by UVR8 in Diverse Species
title Beyond Arabidopsis: Differential UV-B Response Mediated by UVR8 in Diverse Species
title_full Beyond Arabidopsis: Differential UV-B Response Mediated by UVR8 in Diverse Species
title_fullStr Beyond Arabidopsis: Differential UV-B Response Mediated by UVR8 in Diverse Species
title_full_unstemmed Beyond Arabidopsis: Differential UV-B Response Mediated by UVR8 in Diverse Species
title_short Beyond Arabidopsis: Differential UV-B Response Mediated by UVR8 in Diverse Species
title_sort beyond arabidopsis: differential uv-b response mediated by uvr8 in diverse species
topic Plant Science
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591365/
https://www.ncbi.nlm.nih.gov/pubmed/31275337
http://dx.doi.org/10.3389/fpls.2019.00780
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