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Overexpression of a Neuronal Type Adenylyl Cyclase (Type 8) in Sinoatrial Node Markedly Impacts Heart Rate and Rhythm

Heart rate (HR) and HR variability (HRV), predictors of over-all organism health, are widely believed to be driven by autonomic input to the sinoatrial node (SAN), with sympathetic input increasing HR and reducing HRV. However, variability in spontaneous beating intervals in isolated SAN tissue and...

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Detalles Bibliográficos
Autores principales:	Moen, Jack M., Matt, Michael G., Ramirez, Christopher, Tarasov, Kirill V., Chakir, Khalid, Tarasova, Yelena S., Lukyanenko, Yevgeniya, Tsutsui, Kenta, Monfredi, Oliver, Morrell, Christopher H., Tagirova, Syevda, Yaniv, Yael, Huynh, Thanh, Pacak, Karel, Ahmet, Ismayil, Lakatta, Edward G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591434/ https://www.ncbi.nlm.nih.gov/pubmed/31275103 http://dx.doi.org/10.3389/fnins.2019.00615

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