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Loss of MafA and MafB expression promotes islet inflammation
Maf transcription factors are critical regulators of beta-cell function. We have previously shown that reduced MafA expression in human and mouse islets is associated with a pro-inflammatory gene signature. Here, we investigate if the loss of Maf transcription factors induced autoimmune processes in...
Autores principales: | Singh, Tania, Colberg, Jesper K., Sarmiento, Luis, Chaves, Patricia, Hansen, Lisbeth, Bsharat, Sara, Cataldo, Luis R., Dudenhöffer-Pfeifer, Monika, Fex, Malin, Bryder, David, Holmberg, Dan, Sitnicka, Ewa, Cilio, Corrado, Prasad, Rashmi B., Artner, Isabella |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591483/ https://www.ncbi.nlm.nih.gov/pubmed/31235823 http://dx.doi.org/10.1038/s41598-019-45528-x |
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