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Low concentration of rutin treatment might alleviate the cardiotoxicity effect of pirarubicin on cardiomyocytes via activation of PI3K/AKT/mTOR signaling pathway

Cancer is the leading cause of deaths around the world, especially in low- and middle- income countries. Pirarubicin (THP) is an effective drug for treatment of cancer, however, there still exists cardiotoxic effects of THP. Rutin is a kind of antioxidative compound extracted from plants, and might...

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Detalles Bibliográficos
Autores principales:	Fei, Junjie, Sun, Yi, Duan, Yuyin, Xia, Jianming, Yu, Songhua, Ouyang, Peigang, Wang, Teng, Zhang, Guimin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2019
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591567/ https://www.ncbi.nlm.nih.gov/pubmed/31138757 http://dx.doi.org/10.1042/BSR20190546

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