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Glypican-3 promotes cell proliferation and tumorigenesis through up-regulation of β-catenin expression in lung squamous cell carcinoma

As a cell surface proteoglycan anchored by glycosyl-phosphatidylinositol, Glypican-3 (GPC3) is reported to be highly expressed in hepatocellular carcinoma (HCC) and to promote cell proliferation and tumorigenesis through activating Wnt/β-catenin signalling. GPC3 is also overexpressed in lung squamou...

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Detalles Bibliográficos
Autores principales:	Wang, Dongchang, Gao, Yan, Zhang, Yu, Wang, Lifei, Chen, Gang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2019
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591568/ https://www.ncbi.nlm.nih.gov/pubmed/31160489 http://dx.doi.org/10.1042/BSR20181147

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