Fluoroquinolones in Drug-Resistant Tuberculosis: Culture Conversion and Pharmacokinetic/Pharmacodynamic Target Attainment To Guide Dose Selection

Fluoroquinolones are group A drugs in tuberculosis guidelines. We aim to compare the culture conversion between new-generation (levofloxacin and moxifloxacin) and old-generation (ciprofloxacin and ofloxacin) fluoroquinolones, develop pharmacokinetic models, and calculate target attainment for levofl...

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Detalles Bibliográficos
Autores principales: Al-Shaer, Mohammad H., Alghamdi, Wael A., Alsultan, Abdullah, An, Guohua, Ahmed, Shahriar, Alkabab, Yosra, Banu, Sayera, Barbakadze, Ketevan, Houpt, Eric, Kipiani, Maia, Mikiashvili, Lali, Cegielski, J. Peter, Kempker, Russell R., Heysell, Scott K., Peloquin, Charles A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Clinical Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591615/
https://www.ncbi.nlm.nih.gov/pubmed/31061152
http://dx.doi.org/10.1128/AAC.00279-19

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