What Is Excitation/Inhibition and How Is It Regulated? A Case of the Elephant and the Wisemen

The balance between excitation and inhibition in neuronal circuits has drawn more and more attention in recent years, due to its proposed multifaceted functions in the normal neural circuit as well as its potential roles in the etiology of many neurological disorders. Here, we discuss the importance...

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Detalles Bibliográficos
Autores principales: He, Hai-yan, Cline, Hollis T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591655/
https://www.ncbi.nlm.nih.gov/pubmed/31258334
http://dx.doi.org/10.1177/1179069519859371
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author He, Hai-yan
Cline, Hollis T
author_facet He, Hai-yan
Cline, Hollis T
author_sort He, Hai-yan
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description The balance between excitation and inhibition in neuronal circuits has drawn more and more attention in recent years, due to its proposed multifaceted functions in the normal neural circuit as well as its potential roles in the etiology of many neurological disorders. Here, we discuss the importance of clearly defining excitation/inhibition by experimental measurements and the implications of some recent studies to our understanding of the regulation of excitation/inhibition at the neuronal level.
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spelling pubmed-65916552019-06-28 What Is Excitation/Inhibition and How Is It Regulated? A Case of the Elephant and the Wisemen He, Hai-yan Cline, Hollis T J Exp Neurosci Commentary The balance between excitation and inhibition in neuronal circuits has drawn more and more attention in recent years, due to its proposed multifaceted functions in the normal neural circuit as well as its potential roles in the etiology of many neurological disorders. Here, we discuss the importance of clearly defining excitation/inhibition by experimental measurements and the implications of some recent studies to our understanding of the regulation of excitation/inhibition at the neuronal level. SAGE Publications 2019-06-23 /pmc/articles/PMC6591655/ /pubmed/31258334 http://dx.doi.org/10.1177/1179069519859371 Text en © The Author(s) 2019 http://creativecommons.org/licenses/by/4.0/ This article is distributed under the terms of the Creative Commons Attribution 4.0 License (http://www.creativecommons.org/licenses/by/4.0/) which permits any use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Commentary
He, Hai-yan
Cline, Hollis T
What Is Excitation/Inhibition and How Is It Regulated? A Case of the Elephant and the Wisemen
title What Is Excitation/Inhibition and How Is It Regulated? A Case of the Elephant and the Wisemen
title_full What Is Excitation/Inhibition and How Is It Regulated? A Case of the Elephant and the Wisemen
title_fullStr What Is Excitation/Inhibition and How Is It Regulated? A Case of the Elephant and the Wisemen
title_full_unstemmed What Is Excitation/Inhibition and How Is It Regulated? A Case of the Elephant and the Wisemen
title_short What Is Excitation/Inhibition and How Is It Regulated? A Case of the Elephant and the Wisemen
title_sort what is excitation/inhibition and how is it regulated? a case of the elephant and the wisemen
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591655/
https://www.ncbi.nlm.nih.gov/pubmed/31258334
http://dx.doi.org/10.1177/1179069519859371
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