Omics Technologies to Understand Activation of a Biosynthetic Gene Cluster in Micromonospora sp. WMMB235: Deciphering Keyicin Biosynthesis

[Image: see text] DNA sequencing of a large collection of bacterial genomes reveals a wealth of orphan biosynthetic gene clusters (BGCs) with no identifiable products. BGC silencing, for those orphan clusters that are truly silent, rather than those whose products have simply evaded detection and cl...

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Detalles Bibliográficos
Autores principales: Acharya, Deepa, Miller, Ian, Cui, Yusi, Braun, Doug R., Berres, Mark E., Styles, Matthew J., Li, Lingjun, Kwan, Jason, Rajski, Scott R., Blackwell, Helen E., Bugni, Tim S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591704/
https://www.ncbi.nlm.nih.gov/pubmed/31120241
http://dx.doi.org/10.1021/acschembio.9b00223

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