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Adaptive Signature Design- review of the biomarker guided adaptive phase –III controlled design
Genomics having a profound impact on oncology drug development necessitates the use of genomic signatures for therapeutic strategy and emerging medicine proposals. Since its advent in the arena of clinical trials biomarker-related predictive methods for the identification and selection of patient su...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591770/ https://www.ncbi.nlm.nih.gov/pubmed/31289760 http://dx.doi.org/10.1016/j.conctc.2019.100378 |