Topological DNA damage, telomere attrition and T cell senescence during chronic viral infections

BACKGROUND: T cells play a key role in controlling viral infections; however, the underlying mechanisms regulating their functions during human viral infections remain incompletely understood. Here, we used CD4 T cells derived from individuals with chronic viral infections or healthy T cells treated...

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Detalles Bibliográficos
Autores principales: Ji, Yingjie, Dang, Xindi, Nguyen, Lam Ngoc Thao, Nguyen, Lam Nhat, Zhao, Juan, Cao, Dechao, Khanal, Sushant, Schank, Madison, Wu, Xiao Y., Morrison, Zheng D., Zou, Yue, El Gazzar, Mohamed, Ning, Shunbin, Wang, Ling, Moorman, Jonathan P., Yao, Zhi Q.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591813/
https://www.ncbi.nlm.nih.gov/pubmed/31285747
http://dx.doi.org/10.1186/s12979-019-0153-z

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