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Methanol extract of semen Ziziphi Spinosae attenuates ethanol withdrawal anxiety by improving neuropeptide signaling in the central amygdala

BACKGROUND: Ethanol withdrawal (EtOHW) anxiety is a crucial risk factor for alcoholic relapse. The neuropeptide nociceptin/orphanin FQ (N/OFQ) acts upon its receptor (NOP) to antagonize corticotropin-releasing factor (CRF) and elicit anxiolytic actions. Semen Ziziphi Spinosae (SZS), a prototypical h...

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Detalles Bibliográficos
Autores principales:	Li, Li Bo, Kim, Young Woo, Wang, Yu Hua, Bai, Li, Zhu, Xiao Dong, Zhao, Zheng Lin, Lee, Chul Won, Jiao, Yu, Wu, Tong, Cai, Zhen Zhen, Kim, Sang Chan, An, Won G., Yang, Chae Ha, Cui, Guang Cheng, Zhao, Rong Jie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591875/ https://www.ncbi.nlm.nih.gov/pubmed/31234859 http://dx.doi.org/10.1186/s12906-019-2546-0

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