Cargando…

Prevalence of dementia diagnoses not otherwise specified in eight European countries: a cross-sectional cohort study

BACKGROUND: Dementia is a syndrome, with a wide range of symptoms. It is important to have a timely diagnosis during the disease course to reduce the risk of medication errors, enable future care planning for the patient and their relatives thereby optimizing quality of life (QoL). For this reason,...

Descripción completa

Detalles Bibliográficos
Autores principales: Lethin, Connie, Rahm Hallberg, Ingalill, Renom Guiteras, Anna, Verbeek, Hilde, Saks, Kai, Stolt, Minna, Zabalegui, Adelaida, Soto-Martin, Maria, Nilsson, Christer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591914/
https://www.ncbi.nlm.nih.gov/pubmed/31234781
http://dx.doi.org/10.1186/s12877-019-1174-3
_version_ 1783429805095518208
author Lethin, Connie
Rahm Hallberg, Ingalill
Renom Guiteras, Anna
Verbeek, Hilde
Saks, Kai
Stolt, Minna
Zabalegui, Adelaida
Soto-Martin, Maria
Nilsson, Christer
author_facet Lethin, Connie
Rahm Hallberg, Ingalill
Renom Guiteras, Anna
Verbeek, Hilde
Saks, Kai
Stolt, Minna
Zabalegui, Adelaida
Soto-Martin, Maria
Nilsson, Christer
author_sort Lethin, Connie
collection PubMed
description BACKGROUND: Dementia is a syndrome, with a wide range of symptoms. It is important to have a timely diagnosis during the disease course to reduce the risk of medication errors, enable future care planning for the patient and their relatives thereby optimizing quality of life (QoL). For this reason, it is important to avoid a diagnosis of dementia not otherwise specified (DNOS) and instead obtain a diagnosis that reflects the underlying pathology. The aim of this study was to investigate the prevalence and associated factors of DNOS in persons with dementia living at home or in a nursing home. METHODS: This is a cross-sectional cohort study performed in eight European countries. Persons with dementia aged ≥65 years living at home (n = 1223) or in a nursing home (n = 790) were included. Data were collected through personal interviews with questionnaires based on standardised instruments. Specific factors investigated were sociodemographic factors, cognitive function, and mental health, physical health, QoL, resource utilization and medication. Bivariate and backward stepwise multivariate regression analyses were performed. RESULTS: The prevalence of DNOS in the eight participating European countries was 16% (range 1–30%) in persons living at home and 21% (range 1–43%) in persons living in a nursing home. These people are more often older compared to those with a specific dementia diagnosis. In both persons living at home and persons living in a nursing home, DNOS was associated with more severe neuropsychiatric symptoms and less use of anti-dementia medication. In addition, persons with DNOS living at home had more symptoms of depression and less use of antidepressant medication. CONCLUSIONS: The prevalence of DNOS diagnosis is common and seems to vary between European countries. People with DNOS are more often older with more severe neuropsychiatric symptoms and receive fewer anti-dementia medication, anxiolytics and antidepressants. This would support the suggestion that a proper and specific diagnosis of dementia could help the management of their disease.
format Online
Article
Text
id pubmed-6591914
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-65919142019-07-08 Prevalence of dementia diagnoses not otherwise specified in eight European countries: a cross-sectional cohort study Lethin, Connie Rahm Hallberg, Ingalill Renom Guiteras, Anna Verbeek, Hilde Saks, Kai Stolt, Minna Zabalegui, Adelaida Soto-Martin, Maria Nilsson, Christer BMC Geriatr Research Article BACKGROUND: Dementia is a syndrome, with a wide range of symptoms. It is important to have a timely diagnosis during the disease course to reduce the risk of medication errors, enable future care planning for the patient and their relatives thereby optimizing quality of life (QoL). For this reason, it is important to avoid a diagnosis of dementia not otherwise specified (DNOS) and instead obtain a diagnosis that reflects the underlying pathology. The aim of this study was to investigate the prevalence and associated factors of DNOS in persons with dementia living at home or in a nursing home. METHODS: This is a cross-sectional cohort study performed in eight European countries. Persons with dementia aged ≥65 years living at home (n = 1223) or in a nursing home (n = 790) were included. Data were collected through personal interviews with questionnaires based on standardised instruments. Specific factors investigated were sociodemographic factors, cognitive function, and mental health, physical health, QoL, resource utilization and medication. Bivariate and backward stepwise multivariate regression analyses were performed. RESULTS: The prevalence of DNOS in the eight participating European countries was 16% (range 1–30%) in persons living at home and 21% (range 1–43%) in persons living in a nursing home. These people are more often older compared to those with a specific dementia diagnosis. In both persons living at home and persons living in a nursing home, DNOS was associated with more severe neuropsychiatric symptoms and less use of anti-dementia medication. In addition, persons with DNOS living at home had more symptoms of depression and less use of antidepressant medication. CONCLUSIONS: The prevalence of DNOS diagnosis is common and seems to vary between European countries. People with DNOS are more often older with more severe neuropsychiatric symptoms and receive fewer anti-dementia medication, anxiolytics and antidepressants. This would support the suggestion that a proper and specific diagnosis of dementia could help the management of their disease. BioMed Central 2019-06-24 /pmc/articles/PMC6591914/ /pubmed/31234781 http://dx.doi.org/10.1186/s12877-019-1174-3 Text en © The Author(s). 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Article
Lethin, Connie
Rahm Hallberg, Ingalill
Renom Guiteras, Anna
Verbeek, Hilde
Saks, Kai
Stolt, Minna
Zabalegui, Adelaida
Soto-Martin, Maria
Nilsson, Christer
Prevalence of dementia diagnoses not otherwise specified in eight European countries: a cross-sectional cohort study
title Prevalence of dementia diagnoses not otherwise specified in eight European countries: a cross-sectional cohort study
title_full Prevalence of dementia diagnoses not otherwise specified in eight European countries: a cross-sectional cohort study
title_fullStr Prevalence of dementia diagnoses not otherwise specified in eight European countries: a cross-sectional cohort study
title_full_unstemmed Prevalence of dementia diagnoses not otherwise specified in eight European countries: a cross-sectional cohort study
title_short Prevalence of dementia diagnoses not otherwise specified in eight European countries: a cross-sectional cohort study
title_sort prevalence of dementia diagnoses not otherwise specified in eight european countries: a cross-sectional cohort study
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591914/
https://www.ncbi.nlm.nih.gov/pubmed/31234781
http://dx.doi.org/10.1186/s12877-019-1174-3
work_keys_str_mv AT lethinconnie prevalenceofdementiadiagnosesnototherwisespecifiedineighteuropeancountriesacrosssectionalcohortstudy
AT rahmhallbergingalill prevalenceofdementiadiagnosesnototherwisespecifiedineighteuropeancountriesacrosssectionalcohortstudy
AT renomguiterasanna prevalenceofdementiadiagnosesnototherwisespecifiedineighteuropeancountriesacrosssectionalcohortstudy
AT verbeekhilde prevalenceofdementiadiagnosesnototherwisespecifiedineighteuropeancountriesacrosssectionalcohortstudy
AT sakskai prevalenceofdementiadiagnosesnototherwisespecifiedineighteuropeancountriesacrosssectionalcohortstudy
AT stoltminna prevalenceofdementiadiagnosesnototherwisespecifiedineighteuropeancountriesacrosssectionalcohortstudy
AT zabaleguiadelaida prevalenceofdementiadiagnosesnototherwisespecifiedineighteuropeancountriesacrosssectionalcohortstudy
AT sotomartinmaria prevalenceofdementiadiagnosesnototherwisespecifiedineighteuropeancountriesacrosssectionalcohortstudy
AT nilssonchrister prevalenceofdementiadiagnosesnototherwisespecifiedineighteuropeancountriesacrosssectionalcohortstudy