Robust and highly efficient hiPSC generation from patient non-mobilized peripheral blood-derived CD34(+) cells using the auto-erasable Sendai virus vector

BACKGROUND: Disease modeling with patient-derived induced pluripotent stem cells (iPSCs) is a powerful tool for elucidating the mechanisms underlying disease pathogenesis and developing safe and effective treatments. Patient peripheral blood (PB) cells are used for iPSC generation in many cases sinc...

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Detalles Bibliográficos
Autores principales: Okumura, Takashi, Horie, Yumi, Lai, Chen-Yi, Lin, Huan-Ting, Shoda, Hirofumi, Natsumoto, Bunki, Fujio, Keishi, Kumaki, Eri, Okano, Tsubasa, Ono, Shintaro, Tanita, Kay, Morio, Tomohiro, Kanegane, Hirokazu, Hasegawa, Hisanori, Mizoguchi, Fumitaka, Kawahata, Kimito, Kohsaka, Hitoshi, Moritake, Hiroshi, Nunoi, Hiroyuki, Waki, Hironori, Tamaru, Shin-ichi, Sasako, Takayoshi, Yamauchi, Toshimasa, Kadowaki, Takashi, Tanaka, Hiroyuki, Kitanaka, Sachiko, Nishimura, Ken, Ohtaka, Manami, Nakanishi, Mahito, Otsu, Makoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591940/
https://www.ncbi.nlm.nih.gov/pubmed/31234949
http://dx.doi.org/10.1186/s13287-019-1273-2

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