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Spatiotemporal analysis and epidemiological characterization of the human immunodeficiency virus (HIV) in Libya within a twenty five year  period: 1993–2017

BACKGROUND: Infection with the human immunodeficiency virus (HIV) is an alarming problem in North African countries, but few studies have analyzed the geographical distribution of the epidemic. Libya, the second largest country in Africa and with the longest coast on the Mediterranean basin facing E...

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Autores principales: Daw, Mohamed A., Daw, Amina M., Sifennasr, Nadia E. M., Draha, Aisha M., Daw, Ahmed A., Daw, Ali A., Ahmed, Mohamed O., Mokhtar, Ebtisam S., El-Bouzedi, Abdallah Hu., Daw, Ibrahem M., Adam, Samia I., Warrag, Saed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591977/
https://www.ncbi.nlm.nih.gov/pubmed/31238947
http://dx.doi.org/10.1186/s12981-019-0228-0
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author Daw, Mohamed A.
Daw, Amina M.
Sifennasr, Nadia E. M.
Draha, Aisha M.
Daw, Ahmed A.
Daw, Ali A.
Ahmed, Mohamed O.
Mokhtar, Ebtisam S.
El-Bouzedi, Abdallah Hu.
Daw, Ibrahem M.
Adam, Samia I.
Warrag, Saed
author_facet Daw, Mohamed A.
Daw, Amina M.
Sifennasr, Nadia E. M.
Draha, Aisha M.
Daw, Ahmed A.
Daw, Ali A.
Ahmed, Mohamed O.
Mokhtar, Ebtisam S.
El-Bouzedi, Abdallah Hu.
Daw, Ibrahem M.
Adam, Samia I.
Warrag, Saed
author_sort Daw, Mohamed A.
collection PubMed
description BACKGROUND: Infection with the human immunodeficiency virus (HIV) is an alarming problem in North African countries, but few studies have analyzed the geographical distribution of the epidemic. Libya, the second largest country in Africa and with the longest coast on the Mediterranean basin facing Europe, has experienced major outbreaks of HIV infection. Since then, no studies have followed up on the burden of HIV infections. To plan interventions and allocate resources, spatial analysis of HIV/AIDS clusters are required in order to identify epidemic foci and trends in the country. The objective of this study was to assess HIV infection clustering and trends in Libya. METHODS: Information on all recorded HIV/AIDS cases during 1993–2017 were extracted from the National Reporting System. A total of 8015 newly diagnosed HIV cases with address information were included. Spatial autocorrelation and spatial–temporal analysis were used to identify HIV clusters. Spatial correlations between cases and socio-demographic factors were determined using spatial regression. RESULTS: HIV cases steadily increased within the Libyan population, particularly among those aged < 27 years. Spatiotemporal analysis showed marked geographic and temporal variation of HIV infection, particularly during 2005–2012. The risk factors varied from one region to another, and the contribution of injection drug use to infection increased with time. Four clusters in three time periods were identified, three on the Mediterranean coast and one in the south. CONCLUSION: HIV is an emerging problem in Libya, particularly among young adults. The infection rate varies greatly among the regions and districts, particularly within certain definable geographical areas. Effective intervention strategies are needed to contain HIV infections, especially within the endemic areas. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s12981-019-0228-0) contains supplementary material, which is available to authorized users.
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spelling pubmed-65919772019-07-08 Spatiotemporal analysis and epidemiological characterization of the human immunodeficiency virus (HIV) in Libya within a twenty five year  period: 1993–2017 Daw, Mohamed A. Daw, Amina M. Sifennasr, Nadia E. M. Draha, Aisha M. Daw, Ahmed A. Daw, Ali A. Ahmed, Mohamed O. Mokhtar, Ebtisam S. El-Bouzedi, Abdallah Hu. Daw, Ibrahem M. Adam, Samia I. Warrag, Saed AIDS Res Ther Research BACKGROUND: Infection with the human immunodeficiency virus (HIV) is an alarming problem in North African countries, but few studies have analyzed the geographical distribution of the epidemic. Libya, the second largest country in Africa and with the longest coast on the Mediterranean basin facing Europe, has experienced major outbreaks of HIV infection. Since then, no studies have followed up on the burden of HIV infections. To plan interventions and allocate resources, spatial analysis of HIV/AIDS clusters are required in order to identify epidemic foci and trends in the country. The objective of this study was to assess HIV infection clustering and trends in Libya. METHODS: Information on all recorded HIV/AIDS cases during 1993–2017 were extracted from the National Reporting System. A total of 8015 newly diagnosed HIV cases with address information were included. Spatial autocorrelation and spatial–temporal analysis were used to identify HIV clusters. Spatial correlations between cases and socio-demographic factors were determined using spatial regression. RESULTS: HIV cases steadily increased within the Libyan population, particularly among those aged < 27 years. Spatiotemporal analysis showed marked geographic and temporal variation of HIV infection, particularly during 2005–2012. The risk factors varied from one region to another, and the contribution of injection drug use to infection increased with time. Four clusters in three time periods were identified, three on the Mediterranean coast and one in the south. CONCLUSION: HIV is an emerging problem in Libya, particularly among young adults. The infection rate varies greatly among the regions and districts, particularly within certain definable geographical areas. Effective intervention strategies are needed to contain HIV infections, especially within the endemic areas. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s12981-019-0228-0) contains supplementary material, which is available to authorized users. BioMed Central 2019-06-25 /pmc/articles/PMC6591977/ /pubmed/31238947 http://dx.doi.org/10.1186/s12981-019-0228-0 Text en © The Author(s) 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research
Daw, Mohamed A.
Daw, Amina M.
Sifennasr, Nadia E. M.
Draha, Aisha M.
Daw, Ahmed A.
Daw, Ali A.
Ahmed, Mohamed O.
Mokhtar, Ebtisam S.
El-Bouzedi, Abdallah Hu.
Daw, Ibrahem M.
Adam, Samia I.
Warrag, Saed
Spatiotemporal analysis and epidemiological characterization of the human immunodeficiency virus (HIV) in Libya within a twenty five year  period: 1993–2017
title Spatiotemporal analysis and epidemiological characterization of the human immunodeficiency virus (HIV) in Libya within a twenty five year  period: 1993–2017
title_full Spatiotemporal analysis and epidemiological characterization of the human immunodeficiency virus (HIV) in Libya within a twenty five year  period: 1993–2017
title_fullStr Spatiotemporal analysis and epidemiological characterization of the human immunodeficiency virus (HIV) in Libya within a twenty five year  period: 1993–2017
title_full_unstemmed Spatiotemporal analysis and epidemiological characterization of the human immunodeficiency virus (HIV) in Libya within a twenty five year  period: 1993–2017
title_short Spatiotemporal analysis and epidemiological characterization of the human immunodeficiency virus (HIV) in Libya within a twenty five year  period: 1993–2017
title_sort spatiotemporal analysis and epidemiological characterization of the human immunodeficiency virus (hiv) in libya within a twenty five year  period: 1993–2017
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591977/
https://www.ncbi.nlm.nih.gov/pubmed/31238947
http://dx.doi.org/10.1186/s12981-019-0228-0
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