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Antibodies against specific extractable nuclear antigens (ENAs) as diagnostic and prognostic tools and inducers of a profibrotic phenotype in cultured human skin fibroblasts: are they functional?

BACKGROUND: The importance of systemic sclerosis (SSc) autoantibodies for diagnosis has become recognized by their incorporation into the 2013 ACR/EULAR classification criteria. Clear prognostic and phenotypic associations with cutaneous subtype and internal organ involvement have been also describe...

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Detalles Bibliográficos
Autores principales: Corallo, Claudio, Cheleschi, Sara, Cutolo, Maurizio, Soldano, Stefano, Fioravanti, Antonella, Volpi, Nila, Franci, Daniela, Nuti, Ranuccio, Giordano, Nicola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6592008/
https://www.ncbi.nlm.nih.gov/pubmed/31234888
http://dx.doi.org/10.1186/s13075-019-1931-x