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Ocular angiostrongyliasis in Thailand: a retrospective analysis over two decades

PURPOSE: To elucidate the clinical manifestations, management, and visual outcomes of patients with ocular angiostrongyliasis. METHODS: This was a single-center retrospective study of patients with ocular angiostrongyliasis presenting between 1995 and 2017 at Srinagarind Hospital, Khon Kaen, Thailan...

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Autores principales: Sinawat, Suthasinee, Trisakul, Thawinee, Choi, Stephanie, Morley, Michael, Sinawat, Supat, Yospaiboon, Yosanan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6592067/
https://www.ncbi.nlm.nih.gov/pubmed/31417234
http://dx.doi.org/10.2147/OPTH.S204380
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author Sinawat, Suthasinee
Trisakul, Thawinee
Choi, Stephanie
Morley, Michael
Sinawat, Supat
Yospaiboon, Yosanan
author_facet Sinawat, Suthasinee
Trisakul, Thawinee
Choi, Stephanie
Morley, Michael
Sinawat, Supat
Yospaiboon, Yosanan
author_sort Sinawat, Suthasinee
collection PubMed
description PURPOSE: To elucidate the clinical manifestations, management, and visual outcomes of patients with ocular angiostrongyliasis. METHODS: This was a single-center retrospective study of patients with ocular angiostrongyliasis presenting between 1995 and 2017 at Srinagarind Hospital, Khon Kaen, Thailand. Cases were found based on a search of diagnostic codes. A total of 18 patients were diagnosed through identification of the Angiostrongylus cantonensis parasite within the eye. Medical records and ocular photography were reviewed. RESULTS: There were 18 cases, with a mean age of 40.7±14.2 years. All patients had a history of raw food ingestion, such as snails. Most of the patients presented with blurred vision: 13 cases (72.22%) had best-corrected visual acuity of 2/60 or worse. Only one living larva was detected in each case. The size of larvae varied widely from 2.6–12.6 mm in length. Larvae were commonly detected in the vitreous cavity. Although multiple treatment modalities were used, including focal laser, surgery, antihelminthic drugs, and steroid treatment, the majority of cases (70.6%) did not have visual improvement. CONCLUSION: Focal laser is recommended to eradicate subretinal angiostrongyliasis, while laser treatment prior to surgical removal is recommended to eliminate intracameral and intravitreal angiostrongyliasis. Pulse methylprednisolone therapy may be beneficial in cases of acute optic neuritis. The visual prognosis mainly depends on ocular pathology and parasitic migration pathway.
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spelling pubmed-65920672019-08-15 Ocular angiostrongyliasis in Thailand: a retrospective analysis over two decades Sinawat, Suthasinee Trisakul, Thawinee Choi, Stephanie Morley, Michael Sinawat, Supat Yospaiboon, Yosanan Clin Ophthalmol Case Series PURPOSE: To elucidate the clinical manifestations, management, and visual outcomes of patients with ocular angiostrongyliasis. METHODS: This was a single-center retrospective study of patients with ocular angiostrongyliasis presenting between 1995 and 2017 at Srinagarind Hospital, Khon Kaen, Thailand. Cases were found based on a search of diagnostic codes. A total of 18 patients were diagnosed through identification of the Angiostrongylus cantonensis parasite within the eye. Medical records and ocular photography were reviewed. RESULTS: There were 18 cases, with a mean age of 40.7±14.2 years. All patients had a history of raw food ingestion, such as snails. Most of the patients presented with blurred vision: 13 cases (72.22%) had best-corrected visual acuity of 2/60 or worse. Only one living larva was detected in each case. The size of larvae varied widely from 2.6–12.6 mm in length. Larvae were commonly detected in the vitreous cavity. Although multiple treatment modalities were used, including focal laser, surgery, antihelminthic drugs, and steroid treatment, the majority of cases (70.6%) did not have visual improvement. CONCLUSION: Focal laser is recommended to eradicate subretinal angiostrongyliasis, while laser treatment prior to surgical removal is recommended to eliminate intracameral and intravitreal angiostrongyliasis. Pulse methylprednisolone therapy may be beneficial in cases of acute optic neuritis. The visual prognosis mainly depends on ocular pathology and parasitic migration pathway. Dove 2019-06-18 /pmc/articles/PMC6592067/ /pubmed/31417234 http://dx.doi.org/10.2147/OPTH.S204380 Text en © 2019 Sinawat et al. http://creativecommons.org/licenses/by-nc/3.0/ This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Case Series
Sinawat, Suthasinee
Trisakul, Thawinee
Choi, Stephanie
Morley, Michael
Sinawat, Supat
Yospaiboon, Yosanan
Ocular angiostrongyliasis in Thailand: a retrospective analysis over two decades
title Ocular angiostrongyliasis in Thailand: a retrospective analysis over two decades
title_full Ocular angiostrongyliasis in Thailand: a retrospective analysis over two decades
title_fullStr Ocular angiostrongyliasis in Thailand: a retrospective analysis over two decades
title_full_unstemmed Ocular angiostrongyliasis in Thailand: a retrospective analysis over two decades
title_short Ocular angiostrongyliasis in Thailand: a retrospective analysis over two decades
title_sort ocular angiostrongyliasis in thailand: a retrospective analysis over two decades
topic Case Series
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6592067/
https://www.ncbi.nlm.nih.gov/pubmed/31417234
http://dx.doi.org/10.2147/OPTH.S204380
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