Cargando…
Realizing the potential of magnetic resonance image guided radiotherapy in gynaecological and rectal cancer
CT-based radiotherapy workflow is limited by poor soft tissue definition in the pelvis and reliance on rigid registration methods. Current image-guided radiotherapy and adaptive radiotherapy models therefore have limited ability to improve clinical outcomes. The advent of MRI-guided radiotherapy sol...
Autores principales: | , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The British Institute of Radiology.
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6592079/ https://www.ncbi.nlm.nih.gov/pubmed/30933550 http://dx.doi.org/10.1259/bjr.20180670 |
_version_ | 1783429837260587008 |
---|---|
author | White, Ingrid M Scurr, Erica Wetscherek, Andreas Brown, Gina Sohaib, Aslam Nill, Simeon Oelfke, Uwe Dearnaley, David Lalondrelle, Susan Bhide, Shreerang |
author_facet | White, Ingrid M Scurr, Erica Wetscherek, Andreas Brown, Gina Sohaib, Aslam Nill, Simeon Oelfke, Uwe Dearnaley, David Lalondrelle, Susan Bhide, Shreerang |
author_sort | White, Ingrid M |
collection | PubMed |
description | CT-based radiotherapy workflow is limited by poor soft tissue definition in the pelvis and reliance on rigid registration methods. Current image-guided radiotherapy and adaptive radiotherapy models therefore have limited ability to improve clinical outcomes. The advent of MRI-guided radiotherapy solutions provides the opportunity to overcome these limitations with the potential to deliver online real-time MRI-based plan adaptation on a daily basis, a true “plan of the day.” This review describes the application of MRI guided radiotherapy in two pelvic tumour sites likely to benefit from this approach. |
format | Online Article Text |
id | pubmed-6592079 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | The British Institute of Radiology. |
record_format | MEDLINE/PubMed |
spelling | pubmed-65920792020-06-01 Realizing the potential of magnetic resonance image guided radiotherapy in gynaecological and rectal cancer White, Ingrid M Scurr, Erica Wetscherek, Andreas Brown, Gina Sohaib, Aslam Nill, Simeon Oelfke, Uwe Dearnaley, David Lalondrelle, Susan Bhide, Shreerang Br J Radiol Review Article CT-based radiotherapy workflow is limited by poor soft tissue definition in the pelvis and reliance on rigid registration methods. Current image-guided radiotherapy and adaptive radiotherapy models therefore have limited ability to improve clinical outcomes. The advent of MRI-guided radiotherapy solutions provides the opportunity to overcome these limitations with the potential to deliver online real-time MRI-based plan adaptation on a daily basis, a true “plan of the day.” This review describes the application of MRI guided radiotherapy in two pelvic tumour sites likely to benefit from this approach. The British Institute of Radiology. 2019-06 2019-05-13 /pmc/articles/PMC6592079/ /pubmed/30933550 http://dx.doi.org/10.1259/bjr.20180670 Text en © 2019 The Authors. Published by the British Institute of Radiology This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 Unported License http://creativecommons.org/licenses/by/4.0/, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Review Article White, Ingrid M Scurr, Erica Wetscherek, Andreas Brown, Gina Sohaib, Aslam Nill, Simeon Oelfke, Uwe Dearnaley, David Lalondrelle, Susan Bhide, Shreerang Realizing the potential of magnetic resonance image guided radiotherapy in gynaecological and rectal cancer |
title | Realizing the potential of magnetic resonance image guided radiotherapy in gynaecological and rectal cancer |
title_full | Realizing the potential of magnetic resonance image guided radiotherapy in gynaecological and rectal cancer |
title_fullStr | Realizing the potential of magnetic resonance image guided radiotherapy in gynaecological and rectal cancer |
title_full_unstemmed | Realizing the potential of magnetic resonance image guided radiotherapy in gynaecological and rectal cancer |
title_short | Realizing the potential of magnetic resonance image guided radiotherapy in gynaecological and rectal cancer |
title_sort | realizing the potential of magnetic resonance image guided radiotherapy in gynaecological and rectal cancer |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6592079/ https://www.ncbi.nlm.nih.gov/pubmed/30933550 http://dx.doi.org/10.1259/bjr.20180670 |
work_keys_str_mv | AT whiteingridm realizingthepotentialofmagneticresonanceimageguidedradiotherapyingynaecologicalandrectalcancer AT scurrerica realizingthepotentialofmagneticresonanceimageguidedradiotherapyingynaecologicalandrectalcancer AT wetscherekandreas realizingthepotentialofmagneticresonanceimageguidedradiotherapyingynaecologicalandrectalcancer AT browngina realizingthepotentialofmagneticresonanceimageguidedradiotherapyingynaecologicalandrectalcancer AT sohaibaslam realizingthepotentialofmagneticresonanceimageguidedradiotherapyingynaecologicalandrectalcancer AT nillsimeon realizingthepotentialofmagneticresonanceimageguidedradiotherapyingynaecologicalandrectalcancer AT oelfkeuwe realizingthepotentialofmagneticresonanceimageguidedradiotherapyingynaecologicalandrectalcancer AT dearnaleydavid realizingthepotentialofmagneticresonanceimageguidedradiotherapyingynaecologicalandrectalcancer AT lalondrellesusan realizingthepotentialofmagneticresonanceimageguidedradiotherapyingynaecologicalandrectalcancer AT bhideshreerang realizingthepotentialofmagneticresonanceimageguidedradiotherapyingynaecologicalandrectalcancer |