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Realizing the potential of magnetic resonance image guided radiotherapy in gynaecological and rectal cancer

CT-based radiotherapy workflow is limited by poor soft tissue definition in the pelvis and reliance on rigid registration methods. Current image-guided radiotherapy and adaptive radiotherapy models therefore have limited ability to improve clinical outcomes. The advent of MRI-guided radiotherapy sol...

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Autores principales: White, Ingrid M, Scurr, Erica, Wetscherek, Andreas, Brown, Gina, Sohaib, Aslam, Nill, Simeon, Oelfke, Uwe, Dearnaley, David, Lalondrelle, Susan, Bhide, Shreerang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The British Institute of Radiology. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6592079/
https://www.ncbi.nlm.nih.gov/pubmed/30933550
http://dx.doi.org/10.1259/bjr.20180670
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author White, Ingrid M
Scurr, Erica
Wetscherek, Andreas
Brown, Gina
Sohaib, Aslam
Nill, Simeon
Oelfke, Uwe
Dearnaley, David
Lalondrelle, Susan
Bhide, Shreerang
author_facet White, Ingrid M
Scurr, Erica
Wetscherek, Andreas
Brown, Gina
Sohaib, Aslam
Nill, Simeon
Oelfke, Uwe
Dearnaley, David
Lalondrelle, Susan
Bhide, Shreerang
author_sort White, Ingrid M
collection PubMed
description CT-based radiotherapy workflow is limited by poor soft tissue definition in the pelvis and reliance on rigid registration methods. Current image-guided radiotherapy and adaptive radiotherapy models therefore have limited ability to improve clinical outcomes. The advent of MRI-guided radiotherapy solutions provides the opportunity to overcome these limitations with the potential to deliver online real-time MRI-based plan adaptation on a daily basis, a true “plan of the day.” This review describes the application of MRI guided radiotherapy in two pelvic tumour sites likely to benefit from this approach.
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spelling pubmed-65920792020-06-01 Realizing the potential of magnetic resonance image guided radiotherapy in gynaecological and rectal cancer White, Ingrid M Scurr, Erica Wetscherek, Andreas Brown, Gina Sohaib, Aslam Nill, Simeon Oelfke, Uwe Dearnaley, David Lalondrelle, Susan Bhide, Shreerang Br J Radiol Review Article CT-based radiotherapy workflow is limited by poor soft tissue definition in the pelvis and reliance on rigid registration methods. Current image-guided radiotherapy and adaptive radiotherapy models therefore have limited ability to improve clinical outcomes. The advent of MRI-guided radiotherapy solutions provides the opportunity to overcome these limitations with the potential to deliver online real-time MRI-based plan adaptation on a daily basis, a true “plan of the day.” This review describes the application of MRI guided radiotherapy in two pelvic tumour sites likely to benefit from this approach. The British Institute of Radiology. 2019-06 2019-05-13 /pmc/articles/PMC6592079/ /pubmed/30933550 http://dx.doi.org/10.1259/bjr.20180670 Text en © 2019 The Authors. Published by the British Institute of Radiology This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 Unported License http://creativecommons.org/licenses/by/4.0/, which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.
spellingShingle Review Article
White, Ingrid M
Scurr, Erica
Wetscherek, Andreas
Brown, Gina
Sohaib, Aslam
Nill, Simeon
Oelfke, Uwe
Dearnaley, David
Lalondrelle, Susan
Bhide, Shreerang
Realizing the potential of magnetic resonance image guided radiotherapy in gynaecological and rectal cancer
title Realizing the potential of magnetic resonance image guided radiotherapy in gynaecological and rectal cancer
title_full Realizing the potential of magnetic resonance image guided radiotherapy in gynaecological and rectal cancer
title_fullStr Realizing the potential of magnetic resonance image guided radiotherapy in gynaecological and rectal cancer
title_full_unstemmed Realizing the potential of magnetic resonance image guided radiotherapy in gynaecological and rectal cancer
title_short Realizing the potential of magnetic resonance image guided radiotherapy in gynaecological and rectal cancer
title_sort realizing the potential of magnetic resonance image guided radiotherapy in gynaecological and rectal cancer
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6592079/
https://www.ncbi.nlm.nih.gov/pubmed/30933550
http://dx.doi.org/10.1259/bjr.20180670
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