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Gold nanoparticles that target degraded elastin improve imaging and rupture prediction in an AngII mediated mouse model of abdominal aortic aneurysm

Background: Abdominal aortic aneurysms (AAA) are characterized by a progressive disruption and weakening of the extracellular matrix (ECM) leading to dilation of the aorta which can be fatal if not treated. Current diagnostic imaging modalities provides little insight on the varying degree of ECM de...

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Detalles Bibliográficos
Autores principales: Wang, Xiaoying, Lane, Brooks A, Eberth, John F, Lessner, Susan M., Vyavahare, Naren R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6592177/
https://www.ncbi.nlm.nih.gov/pubmed/31281538
http://dx.doi.org/10.7150/thno.34441