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Mutations of the MAPK/TSC/mTOR pathway characterize periventricular glioblastoma with epithelioid SEGA-like morphology–morphological and therapeutic implications

Epithelioid glioblastoma is a recognized glioblastoma variant, recently added to the World Health Organization brain tumor classification, with similar prognosis as the classic variant and B-Raf V600E mutations in 50% of the cases. We identified a new subset of epithelioid glioblastoma with perivent...

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Detalles Bibliográficos
Autores principales: Georgescu, Maria-Magdalena, Li, Yan, Islam, Mohammad Zahidul, Notarianni, Christina, Sun, Hai, Olar, Adriana, Fuller, Gregory N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6592288/
https://www.ncbi.nlm.nih.gov/pubmed/31258848
http://dx.doi.org/10.18632/oncotarget.27005