ETHE1 overexpression promotes SIRT1 and PGC1α mediated aerobic glycolysis, oxidative phosphorylation, mitochondrial biogenesis and colorectal cancer

Ethylmalonic Encephalopathy Protein 1 (ETHE1) is a sulfur dioxygenase that regulates cellular H(2)S levels. We previously demonstrated a significant increase of ETHE1 expression in "single-hit" colon epithelial cells from crypts of patients with Familial Adenomatous Polyposis (FAP). Here,...

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Detalles Bibliográficos
Autores principales: Witherspoon, Mavee, Sandu, Davinder, Lu, Changyuan, Wang, Kehui, Edwards, Robert, Yeung, Anthony, Gelincik, Ozkan, Manfredi, Giovanni, Gross, Steven, Kopelovich, Levy, Lipkin, Steven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6592291/
https://www.ncbi.nlm.nih.gov/pubmed/31258845
http://dx.doi.org/10.18632/oncotarget.26958

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6592291/
https://www.ncbi.nlm.nih.gov/pubmed/31258845
http://dx.doi.org/10.18632/oncotarget.26958

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