Striking Visualization of Diffuse Congenital Nesidioblastosis on Ga-68 DOTATATE PET/CT

“Nesidioblastosis”, later renamed as “persistent hyperinsulinemic hypoglycemia of infancy” presents as either focal or diffuse neo-differentiation of pancreatic Langerhans islet cells from the ductal epithelium. Differentiation of focal disease from diffuse involvement is crucial for optimal disease...

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Autores principales: Canbaz, Fevziye, Aydın, Murat, Meydan, Bilge Can, Bilgici, Meltem Ceyhan, Arıtürk, Ender
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Galenos Publishing 2019
Materias:
Interesting Image
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6592318/
https://www.ncbi.nlm.nih.gov/pubmed/31237140
http://dx.doi.org/10.4274/mirt.galenos.2018.38039
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author Canbaz, Fevziye
Aydın, Murat
Meydan, Bilge Can
Bilgici, Meltem Ceyhan
Arıtürk, Ender
author_facet Canbaz, Fevziye
Aydın, Murat
Meydan, Bilge Can
Bilgici, Meltem Ceyhan
Arıtürk, Ender
author_sort Canbaz, Fevziye
collection PubMed
description “Nesidioblastosis”, later renamed as “persistent hyperinsulinemic hypoglycemia of infancy” presents as either focal or diffuse neo-differentiation of pancreatic Langerhans islet cells from the ductal epithelium. Differentiation of focal disease from diffuse involvement is crucial for optimal disease management. The current methods used to differentiate the two forms pre-operatively are invasive techniques. The definite role of imaging modalities to differentiate diffuse versus focal form has not yet been proven. Herein, we report a 15 day-old infant having diffuse nesidioblastosis, successfully demonstrated by Ga-68 DOTATATE positron emission tomography/computed tomography imaging that was histopathologically confirmed.
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spelling pubmed-65923182019-06-28 Striking Visualization of Diffuse Congenital Nesidioblastosis on Ga-68 DOTATATE PET/CT Canbaz, Fevziye Aydın, Murat Meydan, Bilge Can Bilgici, Meltem Ceyhan Arıtürk, Ender Mol Imaging Radionucl Ther Interesting Image “Nesidioblastosis”, later renamed as “persistent hyperinsulinemic hypoglycemia of infancy” presents as either focal or diffuse neo-differentiation of pancreatic Langerhans islet cells from the ductal epithelium. Differentiation of focal disease from diffuse involvement is crucial for optimal disease management. The current methods used to differentiate the two forms pre-operatively are invasive techniques. The definite role of imaging modalities to differentiate diffuse versus focal form has not yet been proven. Herein, we report a 15 day-old infant having diffuse nesidioblastosis, successfully demonstrated by Ga-68 DOTATATE positron emission tomography/computed tomography imaging that was histopathologically confirmed. Galenos Publishing 2019-06 2019-06-24 /pmc/articles/PMC6592318/ /pubmed/31237140 http://dx.doi.org/10.4274/mirt.galenos.2018.38039 Text en ©Copyright 2019 by Turkish Society of Nuclear Medicine | Molecular Imaging and Radionuclide Therapy published by Galenos Yayınevi. http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Interesting Image
Canbaz, Fevziye
Aydın, Murat
Meydan, Bilge Can
Bilgici, Meltem Ceyhan
Arıtürk, Ender
Striking Visualization of Diffuse Congenital Nesidioblastosis on Ga-68 DOTATATE PET/CT
title Striking Visualization of Diffuse Congenital Nesidioblastosis on Ga-68 DOTATATE PET/CT
title_full Striking Visualization of Diffuse Congenital Nesidioblastosis on Ga-68 DOTATATE PET/CT
title_fullStr Striking Visualization of Diffuse Congenital Nesidioblastosis on Ga-68 DOTATATE PET/CT
title_full_unstemmed Striking Visualization of Diffuse Congenital Nesidioblastosis on Ga-68 DOTATATE PET/CT
title_short Striking Visualization of Diffuse Congenital Nesidioblastosis on Ga-68 DOTATATE PET/CT
title_sort striking visualization of diffuse congenital nesidioblastosis on ga-68 dotatate pet/ct
topic Interesting Image
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6592318/
https://www.ncbi.nlm.nih.gov/pubmed/31237140
http://dx.doi.org/10.4274/mirt.galenos.2018.38039
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