Donor KIR2DS1 reduces the risk of transplant related mortality in HLA-C2 positive young recipients with hematological malignancies treated by myeloablative conditioning

BACKGROUND: Recognition of HLA-C2 group alleles on recipient cells by activating killer immunoglobulin like receptors, KIR2DS1 on donor natural killer cells may lead to increased graft-versus-leukemia effect or immunomodulation in patients treated by allogeneic hematopoietic stem cell transplantatio...

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Detalles Bibliográficos
Autores principales: Tordai, Attila, Bors, Andras, Kiss, Katalin Piroska, Balassa, Katalin, Andrikovics, Hajnalka, Batai, Arpad, Szilvasi, Aniko, Rajczy, Katalin, Inotai, Dora, Torbagyi, Eva, Lengyel, Lilla, Barta, Aniko, Remenyi, Peter, Masszi, Tamas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6592561/
https://www.ncbi.nlm.nih.gov/pubmed/31237928
http://dx.doi.org/10.1371/journal.pone.0218945

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