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Exploring various polygenic risk scores for skin cancer in the phenomes of the Michigan genomics initiative and the UK Biobank with a visual catalog: PRSWeb
Polygenic risk scores (PRS) are designed to serve as single summary measures that are easy to construct, condensing information from a large number of genetic variants associated with a disease. They have been used for stratification and prediction of disease risk. The primary focus of this paper is...
Autores principales: | Fritsche, Lars G., Beesley, Lauren J., VandeHaar, Peter, Peng, Robert B., Salvatore, Maxwell, Zawistowski, Matthew, Gagliano Taliun, Sarah A., Das, Sayantan, LeFaive, Jonathon, Kaleba, Erin O., Klumpner, Thomas T., Moser, Stephanie E., Blanc, Victoria M., Brummett, Chad M., Kheterpal, Sachin, Abecasis, Gonçalo R., Gruber, Stephen B., Mukherjee, Bhramar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6592565/ https://www.ncbi.nlm.nih.gov/pubmed/31194742 http://dx.doi.org/10.1371/journal.pgen.1008202 |
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