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Exploring various polygenic risk scores for skin cancer in the phenomes of the Michigan genomics initiative and the UK Biobank with a visual catalog: PRSWeb

Polygenic risk scores (PRS) are designed to serve as single summary measures that are easy to construct, condensing information from a large number of genetic variants associated with a disease. They have been used for stratification and prediction of disease risk. The primary focus of this paper is...

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Detalles Bibliográficos
Autores principales: Fritsche, Lars G., Beesley, Lauren J., VandeHaar, Peter, Peng, Robert B., Salvatore, Maxwell, Zawistowski, Matthew, Gagliano Taliun, Sarah A., Das, Sayantan, LeFaive, Jonathon, Kaleba, Erin O., Klumpner, Thomas T., Moser, Stephanie E., Blanc, Victoria M., Brummett, Chad M., Kheterpal, Sachin, Abecasis, Gonçalo R., Gruber, Stephen B., Mukherjee, Bhramar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6592565/
https://www.ncbi.nlm.nih.gov/pubmed/31194742
http://dx.doi.org/10.1371/journal.pgen.1008202

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