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Epithelial geometry regulates spindle orientation and progenitor fate during formation of the mammalian epidermis
The control of cell fate through oriented cell division is imperative for proper organ development. Basal epidermal progenitor cells divide parallel or perpendicular to the basement membrane to self-renew or produce differentiated stratified layers, but the mechanisms regulating the choice between d...
Autores principales: | Box, Kimberly, Joyce, Bradley W, Devenport, Danelle |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6592681/ https://www.ncbi.nlm.nih.gov/pubmed/31187731 http://dx.doi.org/10.7554/eLife.47102 |
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